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THU0466 Sexual dysfunction and depression in behcet`s disease – are there differences regarding patient’s origin
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  1. T. Xenitidis1,
  2. A.-C. Pecher1,
  3. T. Schmalen2,
  4. M. Henes3,
  5. J.C. Henes1
  1. 1Centre for Interdisciplinary Clinical Immunology, Rheumatology and Auto-inflammatory Diseases and Department of Internal Medicine II (Oncology, Haematology, Immunology, Rheumatology, Pulmology)
  2. 2University Hospital Tuebingen, Tuebingen, Germany
  3. 3Department of Women’s Health, Women’s University Hospital, University Hospital Tuebingen, Tuebingen, Germany

Abstract

Background Behcet’s disease (BD) is a systemic vasculitis of veins and arteries characterised by oral and genital ulcers (aphthae), skin lesions and uveitis. BD is more common in Middle Eastern countries and Asia but also occurs in Caucasian people.

Objectives Aim of this study was to evaluate the prevalence of sexual dysfunction (SD) in patients with BD as well as analysing differences between patients from different origins. Additionally we investigated the prevalence of depression in both ethnic groups.

Methods This prospective, monocentric study included 106 patients with BD. The International Index of Erectile Function (IIEF) and the Female Sexual Function Index (FSFI) were used for assessing sexual dysfunction and the Beck Depression Inventory (BDI) was used for depression assessment.

Results The mean age of our group was 40.5 years. Half of the patients had Middle Eastern and half Caucasian origin. SD was found in 24.5% of all subjects. Only 6.9% of the male patient‘s group showed signs of SD, while half of the women’s group was suffering from SD (p<0.001). The prevalence for SD was significantly higher in women with Middle Eastern origin compared to women with Caucasian origin (75% vs. 33,3%, p=0.024). Genital ulcers affected 73.6% of all patients. Depression was found in 36.7% of all subjects. Both SD and depression correlated positively in males (p=0.017) and females (p=0.013).

Conclusions SD and depression are very common problems in BD and should be addressed by the treating physician. Both manifestations are intensifying each other.

Disclosure of Interest None declared

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