O015 Il-17 blockade with secukinumab in peripheral spondyloarthritis impacts synovial immunopathology without compromising systemic immune responses

M van de Sande; L van Mens; S Menegatti; I Blijdorp; J de Jong; I Fluri; T Latuhihin; A van Kuijk; L Rogge; N Yeremenko; D Baeten

doi:10.1136/annrheumdis-2018-EWRR2018.15

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O015 Il-17 blockade with secukinumab in peripheral spondyloarthritis impacts synovial immunopathology without compromising systemic immune responses

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M van de Sande 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
L van Mens 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
S Menegatti 2Immunoregulation Unit, Institut Pasteur, Paris, France PubMed articles Google scholar articles
I Blijdorp 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
J de Jong 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
I Fluri 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
T Latuhihin 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
A van Kuijk 3Amsterdam Rheumatology and immunology Centre, Reade, Amsterdam, Netherlands PubMed articles Google scholar articles
L Rogge 2Immunoregulation Unit, Institut Pasteur, Paris, France PubMed articles Google scholar articles
N Yeremenko 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles
D Baeten 1Clinical Immunology and Rheumatology, Amsterdam Rheumatology and immunology Centre, Academic Medical Center-University of Amsterdam, Amsterdam, Netherlands PubMed articles Google scholar articles

Citation

van de Sande M, van Mens L, Menegatti S, et al

O015 Il-17 blockade with secukinumab in peripheral spondyloarthritis impacts synovial immunopathology without compromising systemic immune responses

Annals of the Rheumatic Diseases 2018;77:A8.

Publication history

First published February 21, 2018.

Online issue publication

February 22, 2018

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