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How useful is PET/CT in the evaluation of fever/inflammation of unknown origin? Comment on the article by Schönau et al
  1. Markus Bredemeier
  1. Rheumatology Service at Hospital Nossa Senhora da Conceição, Grupo Hospitalar Conceição (GHC), Porto Alegre, RS, Brazil
  1. Correspondence to Dr Markus Bredemeier, Avenida Francisco Trein, 596, Bloco H, sala 2048, Bairro Cristo Redentor, Porto Alegre, RS, Brazil, 91350-200; markbred{at}

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We read with interest the article by Schönau et al,1 a rare prospective study performed in the setting of fever/inflammation of unknown origin (FUO/IUO). They concluded that positron emitted tomography (PET)/CT is helpful in the diagnosis of the underlying cause of fever/inflammation not elucidated with a preliminary diagnostic work-up. Notwithstanding the merits of the study, there are aspects that may deserve additional comments.

To fulfil the concept of FUO/IUO, the patient has to have a condition whose diagnosis is …

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  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.