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Chondroitin sulfate is superior to placebo in symptomatic knee osteoarthritis
  1. Young Ho Lee
  1. Correspondence to Professor Young Ho Lee, Division of Rheumatology, Korea University Medical Center, Seoul, Republic of Korea; lyhcgh{at}

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I read with great interest the article by Reginster and colleagues1 regarding the effectiveness of chondroitin sulfate (CS) in the treatment of symptomatic knee osteoarthritis (OA). This randomised, double-blind trial demonstrated that pharmaceutical-grade CS is superior to placebo and equivalent to celecoxib in reducing pain and improving function over 6 months in patients with symptomatic knee OA, indicating that this formulation of CS should be considered a first-line treatment in the …

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  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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