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Discussion of Methotrexate Dosage
  1. Sinead A Maguire1,
  2. Claire Marie Sheehy2
  1. 1 Department of Rheumatology, University Hospital Waterford, Waterford, Ireland
  2. 2 Department of Rheumatology, Waterford Regional Hospital, Waterford, Ireland
  1. Correspondence to Dr Sinead A Maguire, Department of Rheumatology SPR, University Hospital Waterford, Waterford, Ireland; sineadmaguire{at}

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We thank Safy et al 1 for their recent article discussing clinical outcomes in early treatment of rheumatoid arthritis with methotrexate and 10 mg daily of prednisolone versus methotrexate alone. This was a post-trial follow-up of the CAMERA II trial, which monitored for radiographic evidence of disease progression, use of biologic disease-modifying antirheumatic drugs (DMARDs) and incidence of glucocorticoid comorbidities. We appreciate the work that …

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  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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