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Antibodies against collagen type II are not a general marker of acute arthritis onset

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  • Contributors VAM and JR designed the study. DvdW, RT, AF and KR contributed with patient samples and clinical information. VAM performed anti-CII ELISA analyses, and JR drafted the text. All authors have read and contributed to the final text and also approved the submitted version.

  • Competing interests None declared.

  • Ethics approval Leiden University Medical Center and Birmingham University, respectively.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement All available data are included in the manuscript.