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Contributors All authors made substantial intellectual contributions to conception of the work, the interpretation of data and approval of the final manuscript. T-YH and Y-MC conceived of the study, generated the original hypothesis, designed the study, and drafted and revised the manuscript. W-NH, Y-DW, C-TL and Y-HC acquired clinical data and analysed data. D-YC conceived of the study, analysed data and revised the manuscript.
Funding This study was supported by a grant from Taichung Veterans General Hospital, Taiwan (TCVGH-1057309C).
Competing interests None declared.
Patient consent Obtained.
Ethics approval Institution Review Board of Taichung Veterans General Hospital.
Provenance and peer review Not commissioned; externally peer reviewed.
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