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Basic and translational research
Extended report
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair

Authors

  • Ruzanna Shkhyan Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Ben Van Handel Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA Department of Stem Cell Research and Regenerative Medicine, University of Southern California, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Jacob Bogdanov Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Siyoung Lee Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Yifan Yu Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA Department of Orthopaedic Surgery, Huai’an First People’s Hospital, Nanjing Medical University, Huai’an, China PubMed articlesGoogle scholar articles
  • Mila Scheinberg Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Nicholas W Banks Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Sean Limfat Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Arthur Chernostrik Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Carlos Eduardo Franciozi Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA Department of Orthoapedic Surgery, Federal University of São Paulo (UNIFESP), São Paulo, Brazil PubMed articlesGoogle scholar articles
  • Mohammad Parvez Alam Drug Discovery Laboratory, Department of Neurology, University of California at Los Angeles, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Varghese John Drug Discovery Laboratory, Department of Neurology, University of California at Los Angeles, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Ling Wu Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Gabriel B Ferguson Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Ali Nsair Department of Medicine, Division of Cardiology, David Geffen School of Medicine (DGSOM), University of California, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Frank A Petrigliano Department of Orthopaedic Surgery, David Geffen School of Medicine (DGSOM), University of California at Los Angeles, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • C Thomas Vangsness Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Kanagasabai Vadivel Department of Orthopaedic Surgery, David Geffen School of Medicine (DGSOM), University of California at Los Angeles, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Paul Bajaj Department of Orthopaedic Surgery, David Geffen School of Medicine (DGSOM), University of California at Los Angeles, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Liming Wang Department of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China PubMed articlesGoogle scholar articles
  • Nancy Q Liu Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA PubMed articlesGoogle scholar articles
  • Denis Evseenko Department of Orthopaedic Surgery, University of Southern California (USC), Los Angeles, California, USA Department of Stem Cell Research and Regenerative Medicine, University of Southern California, Los Angeles, California, USA Department of Orthopaedic Surgery, David Geffen School of Medicine (DGSOM), University of California at Los Angeles, Los Angeles, California, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Denis Evseenko, Stem Cell Research and Regeneration Medicine USC, 1450 Biggy St, Nrt 4509, Los Angeles, CA 90033, USA; evseenko{at}usc.edu
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Citation

Shkhyan R, Van Handel B, Bogdanov J, et al
Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair
Annals of the Rheumatic Diseases 2018;77:760-769.

Publication history

  • Received July 7, 2017
  • Revised January 3, 2018
  • Accepted January 16, 2018
  • First published February 7, 2018.
Online issue publication 
April 12, 2018

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.