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Elevated serum levels of sonic hedgehog are associated with fibrotic and vascular manifestations in systemic sclerosis

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  • Contributors CB and JHWD performed and evaluated experiments and wrote the manuscript. All other authors provided samples and clinical data and commented on the manuscript.

  • Competing interests None declared.

  • Ethics approval Approved by the following universities: Erlangen, Zurich, Basel, Paris, Florence, Giessen, Naples.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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