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Footnotes
LAA and LM contributed equally.
Handling editor Josef S Smolen
Contributors LAA, LarM, SB and MWH conceived the study. MK recruited patients and recorded clinical data. LAA, LarM, LauM, AB, GET, MI, JIRS and SB performed the experiments, analysed the data and generated figures and table with input from KS, AE and MWH. LAA, LarM and MWH wrote the first version of the manuscript, and all authors participated in the editing until its final version.
Funding This study was funded by Vetenskapsrådet, Cancerfonden, Hjärt-Lungfonden, Stockholms Läns Landsting, Karolinska Institutet, Reumatikerförbundet, Norges Forskningsråd, Stiftelsen Konung Gustaf V:s 80-årsfond.
Competing interests None declared.
Patient consent Obtained.
Ethics approval The Regional Ethical Committe Stockholm.
Provenance and peer review Not commissioned; externally peer reviewed.