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Handling editor Josef S Smolen
Contributors Drafting of authors‘ response letter, critical review and final approval: all authors.
Funding This study was funded by NIH-NIAMS, NIH K01AR064351, NIH R21AR068493 and Rheumatology Research Foundation Innovative Research Award.
Competing interests None declared.
Ethics approval IRB at the University of Massachusetts Medical School and Boston University School of Medicine.
Provenance and peer review Commissioned; internally peer reviewed.