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In psoriatic arthritis (PsA), ultrasonography (US) plays a growing role in the differential diagnosis and in monitoring treatment response.1 PsA is a heterogeneous disease with different domains and peculiar sites involved.2 Therefore, a dedicated US composite score is needed to monitor disease activity and to identify structural damage progression. A recently published Systematic Literature Review (SLR) identified only two US scores specifically developed for PsA (ie, 5TPD and PsA-Son) and, although these had a good sensitivity to detect inflammation and a good feasibility, they have not been validated in other series.1 3 4 Recently, the Study Group for US of the Italian Society of Rheumatology promoted the Ultrasound in PSoriatic Arthritis TREAtMent (UPSTREAM) study (registered at ClinicalTrial.gov, NCT03330769). UPSTREAM is a multicentre observational prospective cohort study and it represents the first …
Handling editor Josef S Smolen
Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Not required.
Provenance and peer review Not commissioned; externally peer reviewed.
Collaborators Antonella Adinolfi, Irene Azzolin, Francesca Bandinelli, Alberto Batticciotto, Nicola Boffini, Alessandra Bortoluzzi, Greta Carrara, Francesco Paolo Cavatorta, Giovanni Cagnotto, Marta Caprioli, Michele Colaci, Orazio De Lucia, Andrea Delle Sedie, Valentina Denaro, Andrea Di Matteo, Valentina Di Sabatino, Oscar Massimiliano Epis, Ariela Hoxha, Ilaria Farina, Giuseppe Germanò, Georgios Filippou, Emilio Filippucci, Maria Cristina Focherini, Alessandra Gabba, Luca Idolazzi, Giuliana Maria Concetta La Paglia, Filippo Luccioli, Pierluigi Macchioni, Mirco Magnani, Marco Massarotti, Claudio Mastaglio, Luca Navarini, Simone Parisi, Andrea Picchianti Diamanti, Valentina Picerno, Marco Piras, Francesco Porta, Niccolò Possemato, Immacolata Prevete, Bernd Raffeiner, Roberta Ramonda, Viviana Ravagnani, Daniela Rossi, Silvia Rossi, Palma Scolieri, Gianluca Santoboni, Crescenzio Scioscia, Riccardo Terenzi, Ilaria Tinazzi, Carmela Toscano, Carlo Venditti, Alessandro Volpe, Gentiana Vukatana, Giovanni Zanframundo.
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