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FRI0580 Predict sarcopenia by sonoelastography of quadriceps muscle in osteoporotic patients
  1. Y-C Chen,
  2. C-H Ko
  1. Rheumatology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Province of China


Background Reduced muscle mass had associated with high mortality. So it is urgent for simple techniques to early detection sarcopenia. Our objective was to examine the validity of sonoelastography to predict sarcopenia in osteoporotic patients.

Objectives To evaluate the association of sonoelastography and dual-energy X-ray absorptiometry in patients with sarcopenia and osteoporosis.

Methods We conducted an observational study in Kaohsiung Chang Gang Memorial Hospital. Sarcopenia was determined using a dual-energy X-ray absorptiometry. Osteoporosis was defined through estimated bone mass (BM). Sonoelastography was performed over mid thigh over quadriceps muscle. We measure hardness and elastography ratio of quadriceps over subcutaneous fat tissue. ROC analysis was used to find best cut-off point.

Results A total 47 (23 sarcopenia, 24 non-sarcopenia) osteoporotic patients were enrolled. The mean age was 71.04±9.64 years, and most patients (88.9%) were women. Sonoelastography showed sarcopenia patients had more soft than non-sarcopenia patients, furthermore the elastography ratio of quadriceps over subcutaneous tissue was lower than non-sarcopenia patients. When the cut points determined by receiver operating characteristic (ROC) curve analysis were applied, The best cut-point of hardness was 42.5 (sensitivity, 0.969; 1-specificity, 0.066), while the best cut-point of quadriceps over subcutaneous tissue was 70.5% (sensitivity, 1.00; 1-specificity, 0.079).

Characteristics of study patients

Conclusions Sonoelastography was easily applicable in patients with sarcopenia and osteoporosis. Using hardness content and elastography ratio of quadriceps over subcutaneous ratio render more information of muscle character. Early detection of sarcopenia with sonoelastography in patients with osteoporosis afford future trend of preventive medicine in geriatric patients.


  1. Teber MA, Ogur T, Bozkurt A, Er B, Turan A, Gulbay M, et al. Real-time sonoelastography of the quadriceps tendon in patients undergoing chronic hemodialysis. J Ultrasound Med. 2015;34(4):671–7.


Acknowledgements This study was supported by Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung (grant CMRPG8F1731).

Disclosure of Interest None declared

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