Background The ethnic and geographical differences have been commented on, mainly from European data. We lack large data sets from the eastern part of Europe.

Objectives This study is aimed to present the distribution of vasculitides in the Pediatric and Adult Vasculitis patient groups.

Methods Hacettepe University is one of the main referral centers in the capital of Turkey, serving approximately 470,000 adult and pediatric patients/a year. Hacettepe University Vasculitis Centre (HUVAC) was established to organize a prospective cohort in 2014. All patients starting from October 2014 have been recorded to the database. Additionally electronic patient recording database between October 2014-December 2016 was searched for the patients having any of the 10th revision of the International Statistical Classification of Diseases (ICD)-10 code for the particular vasculitis. The study group of Hacettepe University Vasculitis Centre (HUVAC) re-evaluated the ascertained patients' hospital records to review their diagnosis according to the 2012 revised Chapel Hill nomenclature criteria.

Results A total of 1196 patients had been newly followed in this period. 271 (22.7%) of them were pediatric patients and 31.8% of them were newly diagnosed. The leading vasculitis among adult patients was Behcet's Disease whereas in pediatric patients it was HSP/IgA Vasculitis (Table). Granulomatous polyangiitis was the most common small vessel vasculitis in adults. Takayasu arteritis was more frequent than giant cell arteritis among the adult patients. There was a female predominance in patients with large vessel vasculitis.

During prospective follow up, 22 (1.9%) patients deceased; 7 due to the primary disease, 6 due to infections, 7 due to cardio and cerebrovascular diseases.

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Conclusions Behcet's Disease is the most frequent vasculitis in Turkey and more than half of the patients had organ/system involvements. GPA is the most common small vessel vasculitis whereas Microscopic polyangiitis is very rare. Among children Kawasaki was less and Behçet's disease markedly more when compared to Western European figures. Even though this study is a single-center one, the number of annual admitted patients of our hospital along with more than 2 years-prospective recruitment, reflects the true burden of vasculitides in Turkey, at the cross-roads between Europe and Middle East.

Disclosure of Interest None declared