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Crystal diseases, metabolic bone diseases and bone diseases other than osteoporosis
THU0446 Prevalence and incidence of non-gout crystal arthropathy in southern sweden from the socioeconomic perspective
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  1. M Hameed1,
  2. A Turkiewicz2,
  3. T Saxne3,
  4. L Jacobsson4,
  5. M Englund5,
  6. MC Kapetanovic6
  1. 1Department of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Lund and Skåne University Hospital, Section for Rheumatology in Lund and Malmö, Sweden, Malmö
  2. 2Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund, Sweden
  3. 3Department of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Lund, Section for Rheumatology in Lund and Malmö, Lund
  4. 4Department of Rheumatology & Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg
  5. 5Lund University, Faculty of Medicine, Department of Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit
  6. 6Department of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Lund and Skåne University Hospital, Section for Rheumatology in Lund and Malmö, Sweden, Lund, Sweden

Abstract

Background Recently, we reported the prevalence of gout to be 1.7% among adults in the Skåne region in southern Sweden (1). Few epidemiological data are available on non-gout crystal arthropathy and none for this region.

Objectives The objective of this study was to study the prevalence and incidence of non-gout crystal arthropathy (including chondocalcinosis, acute/subacute/chronic calcium pyrophosphate/hydroxyapatite or other crystal deposition disease) in southern Sweden from the socioeconomic perspective.

Methods The Skåne Healthcare Register includes information on all health care visits with given ICD10-coded diagnoses for all citizens in the region (total population 1.3 million). SHR was searched for all adult (≥18 years) residents in Skåne region in year 2014, who between 1998 and 2014 had received at least one diagnosis of non-gout crystal arthropathy (ICD-10 code M11.0- M11.9) by any physician. The crude point prevalence at December 31st 2014 and the cumulative incidence in the calendar year 2014 were calculated. In addition, we examined the 2014 age- and sex- standardized point prevalence and cumulative incidence of non-gout crystal arthropathy according to occupation (white collar /blue collar with high or low skilled occupations), income (low/middle/high) and level of education (primary school/high school/university).

Results The crude 2014 point prevalence and 2014 cumulative incidence (95% CI) of non-gout crystal arthropathy were 0.23% (0.22% - 0.24%) and 21.5 (18.6–24.3) cases per 100 000 persons at risk, respectively. Compared to women, men had numerically but not significantly higher prevalence (0.26% vs 0.20%) and incidence (24.6 vs 18.5 per 100 000 persons). This pattern remained regardless of age. The mean (SD) age of a person with prevalent non-gout crystal arthropathy was 71.5 (14.4) years. Both prevalence and incidence increased with increasing age and were highest in individuals ≥85 years (prevalence 1.4%), but decreased with years of education. Persons with middle income and blue collar high skilled occupation (e.g. skilled agricultural, forestry and fishery workers and craft and related trades workers) had the highest point prevalence and incidence of non-gout crystal arthroplasty (figure).

Figure

Conclusions Although considerably less prevalent than gout in southern Sweden non-gout crystal arthropathy affects about 0.2% of the adult population, i.e. a similar prevalence as for psoriatic arthritis in the same region. The prevalence increases with age and is highest among individuals aged 85 years or higher. There is a socioeconomic gradient with more affected individuals among people with lower level of education, middle income, and more manual work.

References

  1. Kapetanovic MC, Hameed M, Turkiewicz A, at al. Prevalence and incidence of gout in southern Sweden from the socioeconomic perspective. RMD Open. 2016 Nov 1;2(2):e000326. eCollection 2016.

References

Disclosure of Interest None declared

https://doi.org/10.1136/annrheumdis-2017-eular.3089

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