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SP0148 Pathophysiology of established ra synovitis
  1. B Lauwerys
  1. Department of Rheumatology, Université catolique de Louvain, Brussels, Belgium


Access to synovial tissue through - minimally invasive - synovial biopsy procedures led to the implementation of new translational approaches to our understanding of established RA. In this lecture, we will illustrate how the identification of different synovial pathotypes and related molecular pathways translated into clinically relevant phenotypes, such as disease severity or response to therapy. Validation of these concepts in ongoing large-scale multi-centric trials will be key to the integration of synovial assessment tools in clinical practice.

Disclosure of Interest B. Lauwerys Shareholder of: DNALytics

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