Article Text

Download PDFPDF

AB0805 Panlar consensus. recommendations for the management of osteoarthritis of the hand, hip and knee. short title: pan-american league of associations for rheumatology (PANLAR) osteoarthritis (OA) study group
  1. MJ Quintero1,
  2. H Riera2,
  3. R Espinosa3,
  4. R Souto4,
  5. C Rossi5,
  6. JF Molina6,
  7. J Salas7,
  8. F Radrigan8,
  9. G Reyes9,
  10. L Urioste10,
  11. S Papasidero11,
  12. A Garcia12,
  13. I Iraheta13,
  14. E Nieto2,
  15. R Arape14,
  16. O Castaneda15,
  17. J Angulo16,
  18. I Coimbra17,
  19. LM Franco18,
  20. C Acosta19,
  21. V Liendo20,
  22. R Chacόn-Díaz2,
  23. M Vera2,
  24. A Reginato21,
  25. CV Caballero22,
  26. O Rillo23,
  27. on behalf of (PANLAR) Osteoarthritis (OA) Study Group
  1. 1ReumatologíA
  2. 2Universidad de Los Andes, Mérida, Venezuela, Bolivarian Reoublic of, Mérida, Venezuela, Bolivarian Republic Of
  3. 3Reumatología, Instituto Nacional de Rehabilitaciόn, Ciudad de México, Mexico
  4. 4Cátedra de Reumatología de la Facultad de Medicina de la Universidad de la Republica
  5. 5Cátedra de Reumatología de la Facultad de Medicina de la Universidad de la Republica, Montevideo, Uruguay
  6. 6Rheumatology and the Arthritis Clinical Research Unit at Medicarte, Medellin
  7. 7Grupo de Reumatόlogos del Caribe, Barranquilla, Colombia
  8. 8Universidad Catόlica de Chile, Santiago, Chile
  9. 9Servicio de Reumatología, Hospital Quirúrgico 10 de Octubre, Cerro, la Habana, Cuba
  10. 10Universidad Catόlica San Pablo, Bolivia, Bolivia, Plurinational State Of
  11. 11Servicio de Reumatología del Hospital General de Agudos Dr. E. Tornú, Buenos Aires, Argentina
  12. 12Facultad de Medicina, Universidad Francisco Marroquín
  13. 13Facultad de Medicina, Universidad Francisco Marroquín, Ciudad de Guatemala, Guatemala
  14. 14Centro Clínico la Isabelica, Carabobo, Venezuela, Bolivarian Republic Of
  15. 15Universidad Peruana de Ciencias Aplicadas
  16. 16Universidad Nacional Mayor de San Marcos, Peru, Peru
  17. 17Universidade Estadual de Campinas, Brasil, Brazil
  18. 18Instituto de Urología, Valencia
  19. 19Complejo Hospitalario Universitario “Ruiz y Páez”, Ciudad Bolívar
  20. 20Unidad de investigaciόn Reumatolόgica. Clínica Félix Boada., Caracas, Venezuela, Bolivarian Republic Of
  21. 21Divisiόn of Rheumatology, The Warren Alpert School of Medecine., Providence, United States
  22. 22Universidad de la Sabana, Barranquilla, Colombia
  23. 23Hospital Pirovano, Buenos Aires, Argentina


Background This consensus derives from a previous study of Demographic and Clinical Characteristics by the PANLAR OA study group, reporting significant differences in handling these patients and in which it was evident the need of reaching an agreement in the management of hand, hip and knee OA in Latin America (2)

Objectives The aim is to update the recommendations for the treatment of hand, hip and knee OA by agreeing on key propositions relating to the management of hand, hip and knee OA,identifying and critically appraising research evidence for the effectiveness of the treatments and by generating recommendations based on the available evidence and expert opinion.

Methods Recommendations were developed by a group of 40 specialists made up of rheumatologists and members of other medical disciplines. A systematic review of articles, meta-analyses and guidelines for the management of hand, hip and knee OA published from 2008 and January 2014 was done. The level of evidence and strength of recommendation were classified according to the Jadad scale (3).The level of agreement was established through a Delphi technique.

Results Both “strong” and “conditional” recommendations are given for management of hand, hip and knee OA and non-pharmacological, pharmacological and surgical modalities of treatment are presented according to the different levels of agreement.

Conclusions These recommendations are based on the consensus of clinical experts from a wide range of disciplines considering the available evidence, while balancing the benefits and risks of non-pharmacological, pharmacological and surgical treatment modalities. It is hoped that these recommendations will be utilized by healthcare providers involved in the management of patients with hand, hip and knee OA.


  1. Reginato, Anthony M. et al. Osteoarthritis in Latin America: Study of Demographic and Clinical Characteristics in 3040 Patients. JCR: Journal of Clinical Rheumatology 21.8(2015):391–397.

  2. Jadad, A.R.; Moore R.A.; Carroll D.; Jenkinson C.; Reynolds D.J.M.; Gavaghan D.J.; McQuay H.J.(1996). Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Controlled Clinical Trials 17:1–12. doi: 10.1016/0197-2456(95)00134-4. PMID 8721797.


Disclosure of Interest None declared

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.