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Is MRI a predictive biomarker for clinical response to biologics in rheumatoid arthritis?
  1. Joshua F Baker1,2,3,
  2. Mikkel Østergaard4,5,
  3. Philip G Conaghan6
  1. 1Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA
  2. 2University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania, USA
  3. 3Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  4. 4Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark
  5. 5Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen Denmark
  6. 6NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK
  1. Correspondence to Dr Joshua F Baker, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA; bakerjo{at}uphs.upenn.edu

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We thank Sewerin et al1 for the data they have provided on the predictive role of MRI for clinical response in rheumatoid arthritis (RA). This study follows on from our previous study demonstrating the predictive value of MRI for radiographic damage progression.2 This study by Sewerin builds on the evidence for MRI as an imaging biomarker by demonstrating a prediction of clinical response. The investigators used the German REMISSION-PLUS3 cohort and studied 29 patients …

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