Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Stephen W Scally; Soi-Cheng Law; Yi Tian Ting; Jurgen van Heemst; Jeremy Sokolove; Aaron J Deutsch; E Bridie Clemens; Antonis K Moustakas; George K Papadopoulos; Diane van der Woude; Irene Smolik; Carol A Hitchon; David B Robinson; Elizabeth D Ferucci; Charles N Bernstein; Xiaobo Meng; Vidyanand Anaparti; Tom Huizinga; Katherine Kedzierska; Hugh H Reid; Soumya Raychaudhuri; René E Toes; Jamie Rossjohn; Hani El-Gabalawy; Ranjeny Thomas

doi:10.1136/annrheumdis-2017-211300

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Basic and translational research

Extended report

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Authors

Stephen W Scally Department of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute Monash University, Clayton, Australia PubMed articles Google scholar articles
Soi-Cheng Law The University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Australia PubMed articles Google scholar articles
Yi Tian Ting Department of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute Monash University, Clayton, Australia PubMed articles Google scholar articles
Jurgen van Heemst Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
Jeremy Sokolove Department of Medicine/Immunology and Rheumatology, Stanford University, VA Palo Alto Health Care System, Palo Alto, California PubMed articles Google scholar articles
Aaron J Deutsch Division of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
E Bridie Clemens Department of Microbiology and Immunology, The University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia PubMed articles Google scholar articles
Antonis K Moustakas Faculty of Agricultural Technology, Technological Educational Institute of Ionian Islands, Argostoli Kefalonia, Greece PubMed articles Google scholar articles
George K Papadopoulos Laboratory of Biochemistry and Biophysics, Faculty of Agricultural Technology, Epirus Institute of Technology, Arta, Greece PubMed articles Google scholar articles
Diane van der Woude Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
Irene Smolik Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
Carol A Hitchon Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
David B Robinson Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
Elizabeth D Ferucci Division of Community Health Services, Alaska Native Tribal Health Consortium, Anchorage, Alaska, USA PubMed articles Google scholar articles
Charles N Bernstein Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
Xiaobo Meng Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
Vidyanand Anaparti Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
Tom Huizinga Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
Katherine Kedzierska Department of Microbiology and Immunology, The University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia PubMed articles Google scholar articles
Hugh H Reid Department of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute Monash University, Clayton, Australia PubMed articles Google scholar articles
Soumya Raychaudhuri Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, USAProgram in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, USACenter for Data Sciences, Brigham and Women’s Hospital, Boston, Massachusetts, USAArthritis Research UK Centre for Genetics and Genomics, University of Manchester, Manchester, UK PubMed articles Google scholar articles
René E Toes Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
Jamie Rossjohn Department of Biochemistry and Molecular Biology, Infection and Immunity Program, Biomedicine Discovery Institute Monash University, Clayton, AustraliaInstitute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UKAustralian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Australia PubMed articles Google scholar articles
Hani El-Gabalawy Arthritis Centre, University of Manitoba, Winnipeg, Manitoba, Canada PubMed articles Google scholar articles
Ranjeny Thomas The University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Australia PubMed articles Google scholar articles

Correspondence to Professor Ranjeny Thomas, University of Queensland Diamantina Institute, Level 4, R Wing, Princess Alexandra Hospital, Ipswich Road, Woolloongabba 4102, Queensland, Australia; ranjeny.thomas{at}uq.edu.au

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Citation

Scally SW, Law S, Ting YT, et al

Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis

Annals of the Rheumatic Diseases 2017;76:1915-1923.

Publication history

Received February 13, 2017
Revised May 26, 2017
Accepted July 1, 2017
First published August 11, 2017.

Online issue publication

October 09, 2017

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