Background Gout is one of the most severe and frequent rheumatic diseases. Clinical manifestations of gout arise from uric acid crystal deposition in the musculoskeletal tissue. Many patients with gout have co-morbidities, including hypertension and chronic kidney disease (CKD).
Objectives The goals when treating gout are no different in these patients, but the choice and dosage of drugs may need to be modified. In this study, we aimed to determine whether the chronic kidney disease affects or not the number of the gout attacks.
Methods Consecutively 31 gout patients with CKD (group 1, n=31) and 46 gout patients without CKD (group 2, n=46) were enrolled in the study. The gout attack durations and the number of the gout attack in the last one year were compared among groups.
Results The clinical, demographical and anthropometric variables were presented on table 1. There were no statistical differences in body mass index, use of diuretics and history of nephrolithiasis between two groups (p>0.05 for all). Compared to group 2, group 1 had statistically similar levels of the gout attack durations and the number of the gout attacks in the last one year (both p>0.05). In Bivariate Pearson correlation analysis; gout attack durations and the number of the gout attacks in the last one year were not correlated in any parameters in group 1 (p>0.05 for all).
Conclusions The present study revealed that CKD does not affect the number of the attacks and the attack durations in gout patients. Future large scale multicenter randomized controlled studies are needed and warranted to clarify our results.
Disclosure of Interest None declared
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