Article Text

AB0789 BMD Change around Prosthesis after Uncemented Total Hip Arthroplasty in RA Patients: 15-Year Follow Up
  1. M. Makarov,
  2. S. Makarov,
  3. E. Byalik,
  4. A. Logunov,
  5. G. Vardikova,
  6. M. Lipina,
  7. V. Kolomatsky,
  8. V. Pavlov
  1. orthopaedic department, Nasonova Research Institute of Rheumatology, Moscow, Russian Federation


Background In previous studies we noted that maximum bone loss around total hip prosthesis occurs in first six months after surgery. After six months bone loss becomes slower and in some cases BMD even can increase.

Objectives To study the 15-year follow up changes of BMD in patients with RA.

Methods 282 RA patients were examined at the baseline. At the end of investigation we analyzed 43 patients. DEXA was used for BMD assessment around stem (7 ROIs) and cup (3 ROIs) of prosthesis. First examination was conducted 2 weeks after the operation and repeated at 3, 5, 10 and 15 year after surgery.

Results 3 years after decrease of BMD was -5,8% and -4,9% around stem and cup respectively (p<0,01). By 5 and 10 year the bone loss was not significant (-6,1% and -5,5%; -7,1% and -6,3% around stem and cup respectively). 15 years after surgery we observed significant increase of bone loss (-18,9% and -22,7% around stem and cup respectively (p<0,01))

Conclusions These data supports our opinion of stress remodeling of bone around hip prosthesis. This phenomenon doesn't stop after 1 year but keep on even 15 years after surgery. This means that all RA patients after THA need to use medication to normalize bone remodeling

Disclosure of Interest None declared

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.