Background Prevention of osteoporosis and bone fracture and the relationship between metabolic syndrome and bone density are controversial issues.
Objectives The present study aimed to investigate metabolic syndrome and its components and the association with bone mineral density in post menopausal women referring for bone mineral density (BMD) test.
Methods A total of 143 postmenopausal women with at least one year of menopause experience participated in this cross-sectional study. Demographic and anthropometric characteristics for all participants were collected. Biochemical parameters including fasting blood sugar, Cholesterol (HDL and LDL), triglyceride were also measured prior to BMD test. Afterwards, association between the components of metabolic syndrome and bone densitometry were analyzed using statistical methods.
Results In this study, 72% of participants did not have metabolic syndrome. Among them, 43.4% and 28.7% had osteoporosis and normal density, respectively. Of the remaining28% with metabolic syndrome 12.6% had osteoporosis and 15.4% had normal density. Among the metabolic syndrome components, waist circumference, HDL cholesterol, and waist to hip ratio were found to be significantly associated with bone mass (P<0.05). Osteoporotic women had lower waist circumference and waist to hip ratio and higher HDL than women without osteoporosis. In contrast, women with metabolic syndrome did not have significant differences with women without metabolic syndrome in terms of lumbar and femoral neck densitometry (P>0.05).
Conclusions Results from this study showed that metabolic syndrome and its components did not induce bone mass loss. Due to discrepancies of the studies in this area, it seems that more studies are needed so as to make it possible to take some preventive measures in large scale.
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Acknowledgement The authors gratefully acknowledge the cooperation of the study participants. We thank the subject volunteers and subject involved in data collection
Disclosure of Interest None declared
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