Table of contents

Clinical and epidemiological research

• Concise report: Methotrexate dosage as a source of bias in biological trials in rheumatoid arthritis: a systematic review (18 April, 2016) Free

  Josefina Durán, Margarita Bockorny, Deepan Dalal, Michael LaValley, David T Felson
• Extended report:

  Gene copy-number variations (CNVs) of complement C4 and C4A deficiency in genetic risk and pathogenesis of juvenile dermatomyositis

  (22 October, 2015)

  Katherine E Lintner, Anjali Patwardhan, Lisa G Rider, Rabheh Abdul-Aziz, Yee Ling Wu, Emeli Lundström, Leonid Padyukov, Bi Zhou, Alaaedin Alhomosh, David Newsom, Peter White, Karla B Jones, Terrance P O'Hanlon, Frederick W Miller, Charles H Spencer, Chack Yung Yu
• Extended report: Longitudinal validation of periarticular bone area and 3D shape as biomarkers for knee OA progression? Data from the FNIH OA Biomarkers Consortium (19 October, 2015)

  David Hunter, Michael Nevitt, John Lynch, Virginia Byers Kraus, Jeffrey N Katz, Jamie E Collins, Mike Bowes, Ali Guermazi, Frank W Roemer, Elena Losina
• Extended report: Definition and initial validation of a Lupus Low Disease Activity State (LLDAS) (12 October, 2015)

  Kate Franklyn, Chak Sing Lau, Sandra V Navarra, Worawit Louthrenoo, Aisha Lateef, Laniyati Hamijoyo, C Singgih Wahono, Shun Le Chen, Ou Jin, Susan Morton, Alberta Hoi, Molla Huq, Mandana Nikpour, Eric F Morand
• Extended report: Autoimmune diseases in Adult Life after Childhood Cancer in Scandinavia (ALiCCS) (10 November, 2015)

  Anna Sällfors Holmqvist, Jørgen H Olsen, Lene Mellemkjaer, Stanislaw Garwicz, Lars Hjorth, Christian Moëll, Bengt Månsson, Laufey Tryggvadottir, Henrik Hasle, Jeanette Falck Winther
• Extended report: Clinical significance of worsening versus stable preradiographic MRI lesions in a cohort study of persons at higher risk for knee osteoarthritis (14 October, 2015)

  Leena Sharma, Michael Nevitt, Marc Hochberg, Ali Guermazi, Frank W Roemer, Michel Crema, Charles Eaton, Rebecca Jackson, Kent Kwoh, Jane Cauley, Orit Almagor, Joan S Chmiel
• Extended report: Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment (19 October, 2015)

  Juergen Rech, Axel J Hueber, Stephanie Finzel, Matthias Englbrecht, Judith Haschka, Bernhard Manger, Arnd Kleyer, Michaela Reiser, Jayme Fogagnolo Cobra, Camille Figueiredo, Hans-Peter Tony, Stefan Kleinert, Joerg Wendler, Florian Schuch, Monika Ronneberger, Martin Feuchtenberger, Martin Fleck, Karin Manger, Wolfgang Ochs, Matthias Schmitt-Haendle, Hanns-Martin Lorenz, Hubert Nuesslein, Rieke Alten, Joerg Henes, Klaus Krueger, Georg Schett
• Extended report: Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intra-articular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, double-blinded, randomised, controlled trial (OPERA) (21 October, 2015)

  K Hørslev-Petersen, M L Hetland, L M Ørnbjerg, P Junker, J Pødenphant, T Ellingsen, P Ahlquist, H Lindegaard, A Linauskas, A Schlemmer, M Y Dam, I Hansen, T Lottenburger, C G Ammitzbøll, A Jørgensen, S B Krintel, J Raun, J S Johansen, M Østergaard, K Stengaard-Pedersen, OPERA Study-Group
• Extended report: Tocilizumab in systemic juvenile idiopathic arthritis in a real-world clinical setting: results from 1 year of postmarketing surveillance follow-up of 417 patients in Japan (7 December, 2015)

  Shumpei Yokota, Yasuhiko Itoh, Tomohiro Morio, Hideki Origasa, Naokata Sumitomo, Minako Tomobe, Kunihiko Tanaka, Seiji Minota
• Extended report: Patient-physician discordance in global assessment in early spondyloarthritis and its change over time: the DESIR cohort (22 October, 2015)

  Carole Desthieux, Anna Molto, Benjamin Granger, Alain Saraux, Bruno Fautrel, Laure Gossec
• Extended report: Impact of treatment with biologic DMARDs on the risk of sepsis or mortality after serious infection in patients with rheumatoid arthritis (13 November, 2015)

  A Richter, J Listing, M Schneider, T Klopsch, A Kapelle, J Kaufmann, A Zink, A Strangfeld
• Extended report: Effects of colchicine on risk of cardiovascular events and mortality among patients with gout: a cohort study using electronic medical records linked with Medicare claims (18 November, 2015)

  Daniel H Solomon, Chih-Chin Liu, I-Hsin Kuo, Agnes Zak, Seoyoung C Kim
• Extended report: Incidence and predictors for cardiovascular events in patients with psoriatic arthritis (22 October, 2015)

  Lihi Eder, Ying Wu, Vinod Chandran, Richard Cook, Dafna D Gladman
• Extended report: Genetic variants in ANCA-associated vasculitis: a meta-analysis (6 October, 2015)

  Chinar Rahmattulla, Antien L Mooyaart, Daphne van Hooven, Jan W Schoones, Jan A Bruijn, Olaf M Dekkers, European Vasculitis Genetics Consortium, Ingeborg M Bajema
• Concise report: Antibodies to infliximab in Remicade-treated rheumatic patients show identical reactivity towards biosimilars (10 March, 2016)

  M Begoña Ruiz-Argüello, Ainara Maguregui, Ainhoa Ruiz del Agua, Dora Pascual-Salcedo, Ana Martínez-Feito, Teresa Jurado, Chamaida Plasencia, Alejandro Balsa, Francisca Llinares-Tello, José Rosas, Nerea Torres, Antonio Martínez, Daniel Nagore