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Validity of early MRI structural damage end points and potential impact on clinical trial design in rheumatoid arthritis

Authors

  • Joshua F Baker Philadelphia Veterans’ Affairs Medical Center, Philadelphia, Pennsylvania, USA University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania, USA Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Philip G Conaghan Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK PubMed articlesGoogle scholar articles
  • Paul Emery Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK PubMed articlesGoogle scholar articles
  • Daniel G Baker Janssen Research & Development, LLC., Horsham, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Mikkel Østergaard Department of Clinical Medicine, Faculty of Health and Medical Sciences, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Joshua F Baker, Division of Rheumatology, Department of Medicine, 8 Penn Tower Building, 34th and Civic Center Blvd., Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA; bakerjo{at}uphs.upenn.edu
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Citation

Baker JF, Conaghan PG, Emery P, et al
Validity of early MRI structural damage end points and potential impact on clinical trial design in rheumatoid arthritis

Publication history

  • Received November 3, 2014
  • Revised May 8, 2015
  • Accepted June 6, 2015
  • First published June 19, 2015.
Online issue publication 
May 10, 2016

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