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Effects of colchicine on risk of cardiovascular events among patients with gout: as evidence accrues, is it time for a randomised trial?
  1. Georgios Giannopoulos,
  2. Spyridon Deftereos
  1. Second Department of Cardiology, National and Kapodistrian University of Athens Medical School, Athens, Greece
  1. Correspondence to Dr Georgios Giannopoulos, Second Department of Cardiology, University of Athens Medical School, Athens 12462, Greece; ggiann{at}, georgios.giannopolous{at}

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We read with great interest the paper by Solomon et al1 on the effects of colchicine on risk of cardiovascular events and mortality among patients with gout. The authors should be commended on a well-planned and informative study, which, despite the non-randomised retrospective design, adds valuable evidence on a potential new role of this old drug in cardiovascular disease—a prospect which has come under scrutiny over the past few years.2

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