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A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

Authors

  • Roberto Spreafico Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA SingHealth Translational Immunology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore PubMed articlesGoogle scholar articles
  • Maura Rossetti Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA SingHealth Translational Immunology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore PubMed articlesGoogle scholar articles
  • Jorg van Loosdregt Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA PubMed articlesGoogle scholar articles
  • Carol A Wallace Seattle Children's Hospital and Research Institute, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Margherita Massa Lab Biotecnologie, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy PubMed articlesGoogle scholar articles
  • Silvia Magni-Manzoni Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy PubMed articlesGoogle scholar articles
  • Marco Gattorno Second Pediatrics Division, University of Genoa and G Gaslini Institute, Genova, Italy PubMed articlesGoogle scholar articles
  • Alberto Martini Second Pediatrics Division, University of Genoa and G Gaslini Institute, Genova, Italy PubMed articlesGoogle scholar articles
  • Daniel J Lovell Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA PubMed articlesGoogle scholar articles
  • Salvatore Albani Translational Research Unit, Sanford-Burnham Medical Research Institute, San Diego, California, USA SingHealth Translational Immunology and Inflammation Centre, Singhealth and Duke-NUS Graduate Medical School, Singapore, Singapore PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Roberto Spreafico, SingHealth Translational Immunology and Inflammation Centre, The Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore; roberto.spreafico{at}gmail.com
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Citation

Spreafico R, Rossetti M, van Loosdregt J, et al
A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment

Publication history

  • Received July 7, 2014
  • Revised November 18, 2014
  • Accepted November 18, 2014
  • First published December 12, 2014.

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