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Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation

Authors

  • C C Thornton Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • F Al-Rashed Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK King Fahad Cardiac Centre, King Saud University, Riyadh, Saudi Arabia PubMed articlesGoogle scholar articles
  • D Calay Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • G M Birdsey Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • A Bauer Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • H Mylroie Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • B J Morley University of Bath, Bath, UK PubMed articlesGoogle scholar articles
  • A M Randi Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • D O Haskard Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • J J Boyle Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  • J C Mason Vascular Sciences, Imperial Centre for Translational and Experimental Medicine, National Heart and Lung Institute, Imperial College London, Hammersmith Hospital, London, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Justin Mason, Vascular Sciences, Imperial Centre for Translational & Experimental Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; justin.mason{at}imperial.ac.uk
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Citation

Thornton CC, Al-Rashed F, Calay D, et al
Methotrexate-mediated activation of an AMPK-CREB-dependent pathway: a novel mechanism for vascular protection in chronic systemic inflammation

Publication history

  • Received July 17, 2014
  • Revised October 3, 2014
  • Accepted November 14, 2014
  • First published January 9, 2015.
Online issue publication 
January 11, 2016

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