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Changes in the clinical presentation of patients with rheumatoid arthritis from the early 1990s to the years 2010: earlier identification but more severe patient reported outcomes

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Footnotes

  • Contributors Study concept and design and drafting of the manuscript: WPN, AHMvdH-vM. Acquisition, analysis or interpretation of data and critical revision of the manuscript for important intellectual content: WPN, MPTdW, AB, AHMvdH-vM. Statistical analysis: WPN.

  • Funding This work was supported by the Dutch Arthritis Foundation and the Netherlands Organization for Health Research and Development (Vidi grant).

  • Competing interests None declared.

  • Ethics approval Medical ethical committee of the Leiden University Medical Center.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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