Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production

Yun Deng; Jian Zhao; Daisuke Sakurai; Andrea L Sestak; Vadim Osadchiy; Carl D Langefeld; Kenneth M Kaufman; Jennifer A Kelly; Judith A James; Michelle A Petri; Sang-Cheol Bae; Marta E Alarcón-Riquelme; Graciela S Alarcón; Juan-Manuel Anaya; Lindsey A Criswell; Barry I Freedman; Diane L Kamen; Gary S Gilkeson; Chaim O Jacob; Joan T Merrill; Patrick M Gaffney; Kathy Moser Sivils; Timothy B Niewold; Rosalind Ramsey-Goldman; John D Reveille; R Hal Scofield; Anne M Stevens; Susan A Boackle; Luis M Vilá; I I Woong Sohn; Seung Lee; Deh-Ming Chang; Yeong Wook Song; Timothy J Vyse; John B Harley; Elizabeth E Brown; Jeffrey C Edberg; Robert P Kimberly; Rita M Cantor; Bevra H Hahn; Jennifer M Grossman; Betty P Tsao

doi:10.1136/annrheumdis-2015-208441

Article info

Basic and translational research

Extended report

Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production

Authors

Yun Deng Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Jian Zhao Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Daisuke Sakurai Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Andrea L Sestak Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Vadim Osadchiy Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Carl D Langefeld Department of Biostatistical Sciences, Center for Public Health Genomics, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA PubMed articles Google scholar articles
Kenneth M Kaufman Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA US Department of Veterans Affairs Medical Center, Cincinnati, Ohio, USA PubMed articles Google scholar articles
Jennifer A Kelly Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Judith A James Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Michelle A Petri Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articles Google scholar articles
Sang-Cheol Bae Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea PubMed articles Google scholar articles
Marta E Alarcón-Riquelme Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA Pfizer-Universidad de Granada-Junta de Andalucía Center for Genomics and Oncological Research, Granada, Spain PubMed articles Google scholar articles
Graciela S Alarcón Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA PubMed articles Google scholar articles
Juan-Manuel Anaya Center for Autoimmune Diseases Research (CREA), Universidad del Rosario, Bogotá, Colombia PubMed articles Google scholar articles
Lindsey A Criswell Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California San Francisco, San Francisco, California, USA PubMed articles Google scholar articles
Barry I Freedman Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA PubMed articles Google scholar articles
Diane L Kamen Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA PubMed articles Google scholar articles
Gary S Gilkeson Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA PubMed articles Google scholar articles
Chaim O Jacob Department of Medicine, University of Southern California, Los Angeles, California, USA PubMed articles Google scholar articles
Joan T Merrill Department of Clinical Pharmacology, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Patrick M Gaffney Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Kathy Moser Sivils Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Timothy B Niewold Division of Rheumatology and Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA PubMed articles Google scholar articles
Rosalind Ramsey-Goldman Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA PubMed articles Google scholar articles
John D Reveille Department of Rheumatology and Clinical Immunogenetics, University of Texas Health Science Center at Houston, Houston, Texas, USA PubMed articles Google scholar articles
R Hal Scofield Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA US Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma, USA PubMed articles Google scholar articles
Anne M Stevens Division of Rheumatology, Department of Pediatrics, University of Washington, Seattle, Washington, USA Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Washington, USA PubMed articles Google scholar articles
Susan A Boackle Division of Rheumatology, University of Colorado School of Medicine, Aurora, Colorado, USA US Department of Veterans Affairs Medical Center, Denver, Colorado, USA PubMed articles Google scholar articles
Luis M Vilá Division of Rheumatology, Department of Medicine, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico PubMed articles Google scholar articles
I I Woong Sohn Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea PubMed articles Google scholar articles
Seung Lee Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea PubMed articles Google scholar articles
Deh-Ming Chang Taipei Veterans General Hospital, Taipei City, Taiwan PubMed articles Google scholar articles
Yeong Wook Song Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, and College of Medicine, Medical Research Center, Seoul National University, Seoul, Korea PubMed articles Google scholar articles
Timothy J Vyse Division of Genetics and Molecular Medicine and Immunology, King's College London, London, UK PubMed articles Google scholar articles
John B Harley Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA US Department of Veterans Affairs Medical Center, Cincinnati, Ohio, USA PubMed articles Google scholar articles
Elizabeth E Brown Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA PubMed articles Google scholar articles
Jeffrey C Edberg Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA PubMed articles Google scholar articles
Robert P Kimberly Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA PubMed articles Google scholar articles
Rita M Cantor Department of Human Genetics, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Bevra H Hahn Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Jennifer M Grossman Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles
Betty P Tsao Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA PubMed articles Google scholar articles

Correspondence to Professor Betty P Tsao, Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, 96 Jonathan Lucas St, Clinical Science Bldg Suite 936C, Charleston, SC 29425, USA; tsaob{at}musc.edu

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Citation

Deng Y, Zhao J, Sakurai D, et al

Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production

Annals of the Rheumatic Diseases 2016;75:2007-2013.

Publication history

Received August 18, 2015
Revised November 24, 2015
Accepted December 14, 2015
First published January 18, 2016.

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February 02, 2019

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