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Correspondence response
Response to: ‘Let's stop fooling ourselves. In RA, only ACR/EULAR criteria define remission and equate with absence of disease!’ by Boers
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  1. P Emery1,
  2. C O Bingham III2,
  3. G R Burmester3,
  4. V P Bykerk4,
  5. D E Furst5,
  6. X Mariette6,
  7. D van der Heijde7,
  8. R van Vollenhoven8,
  9. C Arendt9,
  10. I Mountian9,
  11. O Purcaru9,
  12. D Tatla10,
  13. B VanLunen10,
  14. M E Weinblatt11
  1. 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK
  2. 2John Hopkins University, Baltimore, USA
  3. 3Charité - University Medicine, Berlin, Germany
  4. 4Weill Cornell Medical College, Division of Rheumatology, Hospital for Special Surgery, New York, USA
  5. 5Division of Rheumatology, David Geffen School of Medicine at UCLA, Los Angeles, USA
  6. 6Université Paris-Sud, Hôpitaux Universitaires Paris-Sud, AP-HP, INSERM U1184, Le Kremlin Bicêtre, France
  7. 7Leiden University Medical Centre, Leiden, The Netherlands
  8. 8Unit for Clinical Therapy Research, Inflammatory Disease, Karolinska Institute, Stockholm, Sweden
  9. 9UCB Pharma, Brussels, Belgium
  10. 10UCB Pharma, Raleigh, USA
  11. 11Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, USA
  1. Correspondence to Professor Paul Emery, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA, UK; p.emery{at}leeds.ac.uk

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We would like to thank Dr Boers for his critical comments on our study raised in his eLetter,1 and address his concerns regarding our manuscript.2

First, we would like to emphasise that we are in support of the statements in the guidelines issued by the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) in early 2011,3 and acknowledge that the Disease Activity Score 28 erythrocyte sedimentation rate (DAS28(ESR)) based definition of clinical remission (DAS28(ESR) <2.6) is less stringent than the simple disease activity index (SDAI)- and Boolean-based definitions.

However, our manuscript does not make any claims that DAS28(ESR)-based remission is reflective …

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