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Let’s stop fooling ourselves. In RA, only ACR/EULAR criteria define remission and equate with absence of disease!
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I read with interest the report on the C-EARLY study.1 The study has been performed well, and the data support the conclusions. I do, however, take issue with the definition of the chosen endpoint of ‘sustained remission’, that is, a DAS28<2.6 at weeks 40 and 52. First, a period of 12 weeks is arbitrary and, in my view, rather short for a claim of ‘sustained remission’, but this is not my major worry. The new American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) remission criteria for rheumatoid arthritis …