Step-down strategy of spacing TNF-blocker injections for established rheumatoid arthritis in remission: results of the multicentre non-inferiority randomised open-label controlled trial (STRASS: Spacing of TNF-blocker injections in Rheumatoid ArthritiS Study)

Bruno Fautrel; Thao Pham; Toni Alfaiate; Frédérique Gandjbakhch; Violaine Foltz; Jacques Morel; Emmanuelle Dernis; Philippe Gaudin; Olivier Brocq; Elisabeth Solau-Gervais; Jean-Marie Berthelot; Jean-Charles Balblanc; Xavier Mariette; Florence Tubach

doi:10.1136/annrheumdis-2014-206696

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Clinical and epidemiological research

Extended report

Step-down strategy of spacing TNF-blocker injections for established rheumatoid arthritis in remission: results of the multicentre non-inferiority randomised open-label controlled trial (STRASS: Spacing of TNF-blocker injections in Rheumatoid ArthritiS Study)

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Bruno Fautrel Pierre et Marie Curie University—Paris 6, Sorbonne Universités, GRC-08 (EEMOIS), Paris, France APHP, Rheumatology Department, Pitié Salpêtrière Hospital, Paris, France PubMed articles Google scholar articles
Thao Pham Aix-Marseille University, Marseille, France AP-HM, Rheumatology Department, Sainte Marguerite Hospital, Marseille, France PubMed articles Google scholar articles
Toni Alfaiate APHP, Department of Epidemiology and Clinical Research, Hôpital Bichat, Paris, France INSERM CIC-EC 1425, Paris, France PubMed articles Google scholar articles
Frédérique Gandjbakhch Pierre et Marie Curie University—Paris 6, Sorbonne Universités, GRC-08 (EEMOIS), Paris, France APHP, Rheumatology Department, Pitié Salpêtrière Hospital, Paris, France PubMed articles Google scholar articles
Violaine Foltz Pierre et Marie Curie University—Paris 6, Sorbonne Universités, GRC-08 (EEMOIS), Paris, France APHP, Rheumatology Department, Pitié Salpêtrière Hospital, Paris, France PubMed articles Google scholar articles
Jacques Morel Rheumatology Department, Montpellier 1 University, Lapeyronie Hospital, Montpellier, France PubMed articles Google scholar articles
Emmanuelle Dernis Rheumatology Department, Le Mans Hospital, Le Mans, France PubMed articles Google scholar articles
Philippe Gaudin Rheumatology Department, Joseph Fourrier University, Sud Hospital, Grenoble, France PubMed articles Google scholar articles
Olivier Brocq Rheumatology Department, Princess Grace Health Centre, Monaco, Monaco PubMed articles Google scholar articles
Elisabeth Solau-Gervais University of Poitiers, Poitiers, France Rheumatology Department, La Miletrie Hospital, Poitiers, France PubMed articles Google scholar articles
Jean-Marie Berthelot University of Nantes, Nantes, France Rheumatology Department, Hotel-Dieu Hospital, Nantes, France PubMed articles Google scholar articles
Jean-Charles Balblanc Rheumatology Department, Belfort-Montbeliard Health Center, Belfort, France PubMed articles Google scholar articles
Xavier Mariette Paris Sud University—Paris 11, Le Kremlin Bicêtre, France AP-HP, Rheumatology Department, Bicêtre Hospital, Le Kremlin Bicêtre, France PubMed articles Google scholar articles
Florence Tubach Aix-Marseille University, Marseille, France University Paris Diderot, Sorbonne Paris Cité, UMR 1123, Paris, France PubMed articles Google scholar articles

Correspondence to Professor Bruno Fautrel, Université Pierre & Marie Curie (UPMC)—Paris 6, AP-HP, Pitié-Salpêtrière Hospital, Dept of Rheumatology, 83 boulevard de l'Hôpital, Paris F- 75651, Cedex 13, France; bruno.fautrel{at}psl.aphp.fr

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Citation

Fautrel B, Pham T, Alfaiate T, et al

Annals of the Rheumatic Diseases 2016;75:59-67.

Publication history

Received September 27, 2014
Revised May 28, 2015
Accepted June 6, 2015
First published June 23, 2015.

Online issue publication

October 25, 2017

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