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THU0526 Analysis of Bone Mineral Density in Children Aged 0 to 12Y in Guangzhou City
  1. P. Zhang,
  2. Y. Mou,
  3. J. Gu
  1. The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China


Background In the last years, skeletal health has been a public health issues increasingly concerned by most countries in the world. Skeletal development in childhood makes the basis of bone mineral density (BMD) later in life. The normal growth of bone tissue in childhood influences the obtention of peak bone mass, and may decrease the risk of osteoporosis in adulthood. Thus, in order to prevent or avoid skeletal diseases, It is of great importance to focus on bone health in children and to know more about the influencing factors of BMD.

Objectives To explore the children's bone mineral density (BMD) in Guangzhou City.

Methods Quantitative ultrasound was used to check BMD in 2450 children who received physical examination in children health care department of our hospital, SOS value and the corresponding Z-score was recorded. According to Z-score, children were divided into Z-score <-2 (bone strength insufficient severely), -2≤Z-score <-1.5 (bone strength insufficient moderately), -1.5≤Z-score <-1.0 (bone strength insufficient slightly) and Z-score ≥-1.0 (bone strength sufficient) groups. Ultrasonic bone mineral density values of different genders, ages and seasons were analyzed and compared.

Results The distribution of children's BMD SOS value and Z-score accorded with normal distribution. Guangzhou children generally have low BMD and high rate of bone strength insufficiency, especially in infancy, their BMD were mostly at low level, and the smaller the age, the lower BMD Z–score. And in general terms, along with the age increasing,the bone strength Z-score showed a trend of rise. The difference between boys and girls was statistically significant (t =4.314, p=0.000), the girls' Z-score was significantly lower than boys. About the incidence of bone strength insufficiency, boys group was significantly lower than girls, and the difference was statistically significant (χ2=30.746, P=30.746). BMD Z–score was the highest in summer, and the incidence of bone strength insufficiency was lower than other three seasons, the difference was statistically significant (P<0.05).

Conclusions Children in Guangzhou city in China generally have low BMD level and high incidence of bone strength insufficiency, especially in infancy, detection of bone health should be held in all ages, especially from baby.


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Disclosure of Interest None declared

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