Background Gout is considered a metabolic disease and ranked among the diseases connected with obesity, such as an arterial hypertension (AH), coronary artery disease (CAD), stroke, and type 2 diabetes mellitus (WHO, 2000). It has been proven that intake of a considerable quantity of meat products is predictor of acute gouty arthritis. For this reason there is great interest in studying the prevalence of gout among inhabitants of the Republic of Sakha (Yakutia) where a lipid-protein diet prevails. Official data on gout in Yakutia are absent.
Objectives A research project has been initiated to determine the incidence and characteristics of gout in Yakutia from 2007-2012. Patients hospitalized in the department of rheumatology of Yakut City Hospital with gouty arthritis were studied.
Methods Patients are being studied by means of a questionnaire developed by the Institute of Rheumatology (Moscow).
Results 44 patients were registered. Median age of the subjects is 56 years [35-76]. Secondary forms of gout and relapses of disease are common. Accompanying pathology includes: AH in 22 patients, CAD in 7 patient, NIDDM in 4 patients, chronic renal insufficiency in 1 patient, and cardiovascular accidents in 3 patients. Nephrolithiasis in 9 patients only in patients with AH. Metabolic syndrome features in patients with gout: obesity-50%; AH (≥130/85 mm.Hg)-92%; TG (≥1,7mmol/l) - 71%; Glucose (>6,1 mmol/l) – 12,5%.
Conclusions Thus, we observed gout in both elderly patients, predominately men, and some young men, among them there were repeated hospitalizations and multiple risk factors. Results will be used for characterization of the incidence and diagnostic features of gout in the Republic of Sakha (Yakutia) with the goal of standardizing guidelines for diagnosis and treatment of gout.
Nasonova V.A., Barskova V.G. Early diagnosis and treatment of gout - scientifically justified demand to improve of employment and life prognosis of patients. Scientific and Practical Rheumatology 2004;1:5-7.
Acknowledgements Institute of Rheumatology (Moscow), Yakut City Hospital, NEFU (Yakutsk).
Disclosure of Interest None declared
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