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  • The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals

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Basic and translational research
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The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals

Authors

  • Rachel Bayley Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, School of Immunity and Infection, University of Birmingham, Birmingham, UK PubMed articlesGoogle scholar articles
  • Kerry A Kite Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, School of Immunity and Infection, University of Birmingham, Birmingham, UK PubMed articlesGoogle scholar articles
  • Helen M McGettrick Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, School of Immunity and Infection, University of Birmingham, Birmingham, UK PubMed articlesGoogle scholar articles
  • Jacqueline P Smith Department of Rheumatology, Dudley Group of Hospitals NHS Trust, Russell's Hall Hospital, Dudley, West Midlands, UK PubMed articlesGoogle scholar articles
  • George D Kitas Department of Rheumatology, Dudley Group of Hospitals NHS Trust, Russell's Hall Hospital, Dudley, West Midlands, UK PubMed articlesGoogle scholar articles
  • Christopher D Buckley Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, School of Immunity and Infection, University of Birmingham, Birmingham, UK PubMed articlesGoogle scholar articles
  • Stephen P Young Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, School of Immunity and Infection, University of Birmingham, Birmingham, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Stephen P Young, Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, School of Immunity and Infection, University of Birmingham, Birmingham, B15 2TT, UK; s.p.young{at}bham.ac.uk
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Citation

Bayley R, Kite KA, McGettrick HM, et al
The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals
Annals of the Rheumatic Diseases 2015;74:1588-1595.

Publication history

  • Received October 22, 2013
  • Revised February 13, 2014
  • Accepted March 1, 2014
  • First published March 24, 2014.
Online issue publication 
July 09, 2015

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