The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals

Rachel Bayley; Kerry A Kite; Helen M McGettrick; Jacqueline P Smith; George D Kitas; Christopher D Buckley; Stephen P Young

doi:10.1136/annrheumdis-2013-204796

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Basic and translational research

Extended report

The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals

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	Abstract	Full	Pdf
Mar 2014	361	35	49
Apr 2014	152	33	27
May 2014	73	42	21
Jun 2014	52	19	20
Jul 2014	67	4	12
Aug 2014	29	5	5
Sep 2014	38	11	17
Oct 2014	48	14	17
Nov 2014	49	4	10
Dec 2014	34	13	16
Jan 2015	37	8	5
Feb 2015	33	5	8
Mar 2015	42	16	9
Apr 2015	17	8	8
May 2015	23	2	8
Jun 2015	34	9	5
Jul 2015	516	22	47
Aug 2015	285	18	20
Sep 2015	192	10	12
Oct 2015	63	7	8
Nov 2015	74	11	14
Dec 2015	58	5	5
Jan 2016	43	6	12
Feb 2016	34	10	9
Mar 2016	42	6	3
Apr 2016	37	4	5
May 2016	41	3	4
Jun 2016	29	7	4
Jul 2016	36	11	11
Aug 2016	39	1	2
Sep 2016	28	10	8
Oct 2016	50	16	8
Nov 2016	45	21	12
Dec 2016	57	2	3
Jan 2017	38	11	10
Feb 2017	48	16	11
Mar 2017	38	12	5
Apr 2017	27	12	2
May 2017	22	6	4
Jun 2017	36	9	4
Jul 2017	31	3	3
Aug 2017	65	8	5
Sep 2017	70	1	2
Oct 2017	63	6	2
Nov 2017	63	5	2
Dec 2017	47	6	2
Jan 2018	68	6	1
Feb 2018	70	6	9
Mar 2018	100	17	5
Apr 2018	56	6	4
May 2018	46	6	2
Jun 2018	48	3	2
Jul 2018	43	6	5
Aug 2018	41	2	1
Sep 2018	40	3	3
Oct 2018	42	4	3
Nov 2018	52	7	1
Dec 2018	38	0	3
Jan 2019	41	5	3
Feb 2019	32	4	2
Mar 2019	32	2	2
Apr 2019	38	7	3
May 2019	17	3	1
Jun 2019	22	0	0
Jul 2019	13	1	0
Aug 2019	19	4	1
Sep 2019	29	4	1
Oct 2019	64	8	2
Nov 2019	43	5	2
Dec 2019	58	5	5
Jan 2020	47	3	10
Feb 2020	15	1	1
Mar 2020	29	0	1
Apr 2020	23	1	1
May 2020	47	1	2
Jun 2020	35	2	1
Jul 2020	26	0	2
Aug 2020	25	0	0
Sep 2020	58	1	0
Oct 2020	67	2	1
Nov 2020	43	2	1
Dec 2020	28	2	3
Jan 2021	33	1	0
Feb 2021	56	1	0
Mar 2021	59	4	1
Apr 2021	47	3	3
May 2021	7	2	1
Jun 2021	4	4	0
Jul 2021	4	4	4
Aug 2021	3	0	0
Sep 2021	3	3	1
Oct 2021	66	4	3
Nov 2021	44	4	3
Dec 2021	63	5	2
Jan 2022	44	9	1
Feb 2022	22	0	0
Mar 2022	33	1	0
Apr 2022	70	4	2
May 2022	83	5	5
Jun 2022	57	2	1
Jul 2022	33	6	1
Aug 2022	44	1	1
Sep 2022	69	2	1
Oct 2022	79	11	6
Nov 2022	82	0	1
Dec 2022	54	3	12
Jan 2023	55	9	4
Feb 2023	91	3	3
Total	6006	713	616

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