Table of contents

Clinical and epidemiological research

• Extended report: The effect of comedication with conventional synthetic disease modifying antirheumatic drugs on TNF inhibitor drug survival in patients with ankylosing spondylitis and undifferentiated spondyloarthritis: results from a nationwide prospective study (20 February, 2015) Free

  Elisabeth Lie, Lars Erik Kristensen, Helena Forsblad-d'Elia, Tatiana Zverkova-Sandström, Johan Askling, Lennart T Jacobsson, for the ARTIS Study Group
• Extended report: Rituximab versus an alternative TNF inhibitor in patients with rheumatoid arthritis who failed to respond to a single previous TNF inhibitor: SWITCH-RA, a global, observational, comparative effectiveness study (17 January, 2014)

  P Emery, J E Gottenberg, A Rubbert-Roth, P Sarzi-Puttini, D Choquette, V M Martínez Taboada, L Barile-Fabris, R J Moots, A Ostor, A Andrianakos, E Gemmen, C Mpofu, C Chung, L Hinsch Gylvin, A Finckh
• Extended report: Does spinal MRI add incremental diagnostic value to MRI of the sacroiliac joints alone in patients with non-radiographic axial spondyloarthritis? (22 January, 2014)

  Ulrich Weber, Veronika Zubler, Zheng Zhao, Robert GW Lambert, Stanley M Chan, Susanne J Pedersen, Mikkel Østergaard, Kaspar Rufibach, Walter P Maksymowych
• Extended report: Incidence and mortality rates of biopsy-proven giant cell arteritis in southern Sweden (17 January, 2014)

  Aladdin J Mohammad, Jan-Åke Nilsson, Lennart TH Jacobsson, Peter A Merkel, Carl Turesson
• Extended report: The effect of disease duration and disease activity on the risk of cardiovascular disease in rheumatoid arthritis patients (23 January, 2014)

  Elke E A Arts, Jaap Fransen, Alfons A den Broeder, Calin D Popa, Piet L C M van Riel
• Extended report: The patient perspective on remission in rheumatoid arthritis: ‘You've got limits, but you're back to being you again’ (12 February, 2014)

  Lilian H D van Tuyl, Sarah Hewlett, Martina Sadlonova, Bev Davis, Caroline Flurey, Wijnanda Hoogland, John Kirwan, Tessa Sanderson, Dirkjan van Schaardenburg, Marieke Scholte-Voshaar, Josef Smolen, Tanja Stamm, Maarten Boers
• Extended report: Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients (24 January, 2014)

  R Cervera, R Serrano, G J Pons-Estel, L Ceberio-Hualde, Y Shoenfeld, E de Ramón, V Buonaiuto, S Jacobsen, M M Zeher, T Tarr, A Tincani, M Taglietti, G Theodossiades, E Nomikou, M Galeazzi, F Bellisai, P L Meroni, R H W M Derksen, P G D de Groot, M Baleva, M Mosca, S Bombardieri, F Houssiau, J-C Gris, I Quéré, E Hachulla, C Vasconcelos, A Fernández-Nebro, M Haro, Z Amoura, M Miyara, M Tektonidou, G Espinosa, M L Bertolaccini, M A Khamashta
• Extended report: The number of flares patients experience impacts on damage accrual in systemic lupus erythematosus: data from a multiethnic Latin American cohort (13 February, 2014)

  Manuel F Ugarte-Gil, Eduardo Acevedo-Vásquez, Graciela S Alarcón, Cesar A Pastor-Asurza, José L Alfaro-Lozano, Jorge M Cucho-Venegas, Maria I Segami, Daniel Wojdyla, Enrique R Soriano, Cristina Drenkard, João Carlos Brenol, Ana Carolina de Oliveira e Silva Montandon, Lilian T Lavras Costallat, Loreto Massardo, José F Molina-Restrepo, Marlene Guibert-Toledano, Luis H Silveira, Mary Carmen Amigo, Leonor A Barile-Fabris, Rosa Chacón-Díaz, Maria H Esteva-Spinetti, Guillermo J Pons-Estel, Gerald McGwin, Bernardo A Pons-Estel
• Extended report: Weight change and change in tibial cartilage volume and symptoms in obese adults (11 February, 2014)

  Andrew J Teichtahl, Anita E Wluka, Stephanie K Tanamas, Yuanyuan Wang, Boyd J Strauss, Joseph Proietto, John B Dixon, Graeme Jones, Andrew Forbes, Flavia M Cicuttini
• Extended report: Relationship between structural joint damage and urate deposition in gout: a plain radiography and dual-energy CT study (12 February, 2014)

  Nicola Dalbeth, Opetaia Aati, Ramanamma Kalluru, Gregory D Gamble, Anne Horne, Anthony J Doyle, Fiona M McQueen
• Extended report: Efficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial (18 February, 2014)

  Gerd-Rűdiger Burmester, Alan J Kivitz, Hartmut Kupper, Udayasankar Arulmani, Stefan Florentinus, Sandra L Goss, Suchitrita S Rathmann, Roy M Fleischmann
• Extended report: Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis (13 February, 2014)

  Muhammad Haroon, Phil Gallagher, Oliver FitzGerald
• Extended report: Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN) (18 February, 2014)

  Joachim Sieper, Jürgen Braun, Jonathan Kay, Salvatore Badalamenti, Allen R Radin, Lixia Jiao, Stefano Fiore, Tanya Momtahen, George D Yancopoulos, Neil Stahl, Robert D Inman
• Extended report: MOR103, a human monoclonal antibody to granulocyte–macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial (17 February, 2014)

  Frank Behrens, Paul P Tak, Mikkel Østergaard, Rumen Stoilov, Piotr Wiland, Thomas W Huizinga, Vadym Y Berenfus, Stoyanka Vladeva, Juergen Rech, Andrea Rubbert-Roth, Mariusz Korkosz, Dmitriy Rekalov, Igor A Zupanets, Bo J Ejbjerg, Jens Geiseler, Julia Fresenius, Roman P Korolkiewicz, Arndt J Schottelius, Harald Burkhardt
• Extended report: Risk of hospitalised infection in rheumatoid arthritis patients receiving biologics following a previous infection while on treatment with anti-TNF therapy (7 March, 2014)

  Huifeng Yun, Fenglong Xie, Elizabeth Delzell, Lang Chen, Emily B Levitan, James D Lewis, Kenneth G Saag, Timothy Beukelman, Kevin Winthrop, John W Baddley, Jeffrey R Curtis
• Extended report: Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study (25 March, 2014)

  Tim Bongartz, Katrina N Glazebrook, Steven J Kavros, Naveen S Murthy, Stephen P Merry, Walter B Franz, Clement J Michet, Barath M Akkara Veetil, John M Davis, Thomas G Mason, Kenneth J Warrington, Steven R Ytterberg, Eric L Matteson, Cynthia S Crowson, Shuai Leng, Cynthia H McCollough
• Extended report:

  Comparison of Tripterygium wilfordii Hook F with methotrexate in the treatment of active rheumatoid arthritis (TRIFRA): a randomised, controlled clinical trial

  (14 April, 2014)

  Qian-wen Lv, Wen Zhang, Qun Shi, Wen-jie Zheng, Xin Li, Hua Chen, Qing-jun Wu, Wan-lan Jiang, Hong-bin Li, Lu Gong, Wei Wei, Hui Liu, Ai-jing Liu, Hong-tao Jin, Jun-xiang Wang, Xiu-mei Liu, Zhen-bin Li, Bin Liu, Min Shen, Qian Wang, Xiang-ni Wu, Di Liang, Yu-feng Yin, Yun-yun Fei, Jing-mei Su, Li-dan Zhao, Ying Jiang, Jing Li, Fu-lin Tang, Feng-chun Zhang, Peter E Lipsky, Xuan Zhang
• Extended report: Risk of solid cancer in patients exposed to anti-tumour necrosis factor therapy: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis (31 March, 2014)

  Louise K Mercer, Mark Lunt, Audrey L S Low, William G Dixon, Kath D Watson, Deborah P M Symmons, Kimme L Hyrich, BSRBR Control Centre Consortium
• Extended report: Cost-effectiveness of infliximab versus conventional combination treatment in methotrexate-refractory early rheumatoid arthritis: 2-year results of the register-enriched randomised controlled SWEFOT trial (15 April, 2014)

  Jonas K Eriksson, Johan A Karlsson, Johan Bratt, Ingemar F Petersson, Ronald F van Vollenhoven, Sofia Ernestam, Pierre Geborek, Martin Neovius
• Extended report: Pretreatment multi-biomarker disease activity score and radiographic progression in early RA: results from the SWEFOT trial (8 May, 2014)

  Karen Hambardzumyan, Rebecca Bolce, Saedis Saevarsdottir, Scott E Cruickshank, Eric H Sasso, David Chernoff, Kristina Forslind, Ingemar F Petersson, Pierre Geborek, Ronald F van Vollenhoven
• Extended report: Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial (16 May, 2014)

  Hermine I Brunner, Nicolino Ruperto, Zbigniew Zuber, Caroline Keane, Olivier Harari, Andrew Kenwright, Peng Lu, Ruben Cuttica, Vladimir Keltsev, Ricardo M Xavier, Inmaculada Calvo, Irina Nikishina, Nadina Rubio-Pérez, Ekaterina Alexeeva, Vyacheslav Chasnyk, Gerd Horneff, Violetta Opoka-Winiarska, Pierre Quartier, Clovis A Silva, Earl Silverman, Alberto Spindler, Eileen Baildam, M Luz Gámir, Alan Martin, Christoph Rietschel, Daniel Siri, Elzbieta Smolewska, Daniel Lovell, Alberto Martini, Fabrizio De Benedetti, for the Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)
• Extended report: Systemic inflammation and cardiovascular risk factors predict rapid progression of atherosclerosis in rheumatoid arthritis (20 May, 2014)

  Inmaculada del Rincón, Joseph F Polak, Daniel H O'Leary, Daniel F Battafarano, John M Erikson, Jose F Restrepo, Emily Molina, Agustín Escalante
• Extended report: Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database (30 June, 2014)

  Britta Maurer, Nicole Graf, Beat A Michel, Ulf Müller-Ladner, László Czirják, Christopher P Denton, Alan Tyndall, Carola Metzig, Vivian Lanius, Dinesh Khanna, Oliver Distler, EUSTAR co-authors
• Extended report: How much does Disease Activity Score in 28 joints ESR and CRP calculations underestimate disease activity compared with the Simplified Disease Activity Index? (20 August, 2014)

  Roy Fleischmann, Désirée van der Heijde, Andrew S Koenig, Ronald Pedersen, Annette Szumski, Lisa Marshall, Eustratios Bananis
• Extended report: Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17 (30 September, 2014)

  S Lightman, S R J Taylor, C Bunce, H Longhurst, W Lynn, R Moots, M Stanford, O Tomkins-Netzer, D Yang, V L Calder, D O Haskard
• Extended report: Development of patient-centred standards of care for osteoarthritis in Europe: the eumusc.net-project (21 November, 2014)

  Michaela A Stoffer, Josef S Smolen, Anthony Woolf, Ales Ambrozic, Florian Berghea, Annelies Boonen, Ailsa Bosworth, Loreto Carmona, Maxime Dougados, Maarten de Wit, Josephine Erwin, Veronika Fialka-Moser, Ruxandra Ionescu, Anne-Maree Keenan, Estibaliz Loza, Rikke H Moe, Rolf Greiff, Pawel Olejnik, Ingemar F Petersson, Anne-Christine Rat, Blaz Rozman, Britta Strömbeck, Lorraine Tanner, Till Uhlig, Theodora P M Vliet Vlieland, Tanja A Stamm, The eumusc.net WP 5 Expert Panel
• Extended report: Discontinuation of tumour necrosis factor inhibitors in patients with rheumatoid arthritis in low-disease activity: persistent benefits. Data from the Corrona registry (3 December, 2014)

  Arthur Kavanaugh, Susan J Lee, Jeffrey R Curtis, Jeffrey D Greenberg, Joel M Kremer, Lilian Soto, Carol J Etzel, Vanessa Cox, Kazuki Yoshida, George W Reed, Daniel H Solomon
• Extended report: MRI assessment of early response to certolizumab pegol in rheumatoid arthritis: a randomised, double-blind, placebo-controlled phase IIIb study applying MRI at weeks 0, 1, 2, 4, 8 and 16 (15 December, 2014)

  M Østergaard, L T H Jacobsson, C Schaufelberger, M Sejer Hansen, J W J Bijlsma, A Dudek, M Rell-Bakalarska, F Staelens, R Haake, B Sundman-Engberg, H Bliddal
• Extended report: A randomised trial of a brace for patellofemoral osteoarthritis targeting knee pain and bone marrow lesions (16 January, 2015)

  Michael J Callaghan, Matthew J Parkes, Charles E Hutchinson, Andrew D Gait, Laura M Forsythe, Elizabeth J Marjanovic, Mark Lunt, David T Felson
• Extended report: Rituximab for IgG4-related disease: a prospective, open-label trial (9 February, 2015)

  Mollie N Carruthers, Mark D Topazian, Arezou Khosroshahi, Thomas E Witzig, Zachary S Wallace, Philip A Hart, Vikram Deshpande, Thomas C Smyrk, Suresh Chari, John H Stone
• Concise report: Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis: 2-year results of a randomised trial (4 March, 2015)

  Rachel B Jones, Shunsuke Furuta, Jan Willem Cohen Tervaert, Thomas Hauser, Raashid Luqmani, Matthew D Morgan, Chen Au Peh, Caroline O Savage, Marten Segelmark, Vladimir Tesar, Pieter van Paassen, Michael Walsh, Kerstin Westman, David RW Jayne, for the European Vasculitis Society (EUVAS)
• Concise report: Differences and similarities in rheumatology specialty training programmes across European countries (6 March, 2015)

  Francisca Sivera, Sofia Ramiro, Nada Cikes, Maxime Dougados, Laure Gossec, Tore K Kvien, Ingrid E Lundberg, Peter Mandl, Arumugam Moorthy, Sonia Panchal, José A P da Silva, Johannes W Bijlsma
• Extended report: Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group (17 January, 2014)

  Suzana Jordan, Jörg H W Distler, Britta Maurer, Dörte Huscher, Jacob M van Laar, Yannick Allanore, Oliver Distler
• Extended report: An extra dose of rituximab improves clinical response in rheumatoid arthritis patients with initial incomplete B cell depletion: a randomised controlled trial (17 January, 2014)

  Edward M Vital, Shouvik Dass, Maya H Buch, Andrew C Rawstron, Paul Emery
• Extended report: Efficacy and safety of tanezumab monotherapy or combined with non-steroidal anti-inflammatory drugs in the treatment of knee or hip osteoarthritis pain (13 March, 2014)

  Thomas J Schnitzer, Evan F Ekman, Egilius L H Spierings, H Scott Greenberg, Michael D Smith, Mark T Brown, Christine R West, Kenneth M Verburg
• Extended report: Are patients with rheumatoid arthritis still at an increased risk of tuberculosis and what is the role of biological treatments? (7 March, 2014)

  Elizabeth V Arkema, Jerker Jonsson, Eva Baecklund, Judith Bruchfeld, Nils Feltelius, Johan Askling
• Extended report: Reference intervals of spinal mobility measures in normal individuals: the mobility study (24 March, 2014)

  Sofia Ramiro, Astrid van Tubergen, Carmen Stolwijk, Désirée van der Heijde, Patrick Royston, Robert Landewé
• Extended report: Characterising arthralgia in the preclinical phase of rheumatoid arthritis using MRI (9 April, 2014)

  Hanna W van Steenbergen, Jessica A B van Nies, Tom W J Huizinga, Johan L Bloem, Monique Reijnierse, Annette H M van der Helm-van Mil
• Extended report: Intensive combination treatment regimens, including prednisolone, are effective in treating patients with early rheumatoid arthritis regardless of additional etanercept: 1-year results of the COBRA-light open-label, randomised, non-inferiority trial (12 May, 2014)

  Marieke M ter Wee, Debby den Uyl, Maarten Boers, Pit Kerstens, Mike Nurmohamed, Dirkjan van Schaardenburg, Alexandre E Voskuyl, Willem F Lems
• Extended report: Efficacy of TNFα blockers in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a meta-analysis (9 April, 2014)

  Johanna Callhoff, Joachim Sieper, Anja Weiß, Angela Zink, Joachim Listing