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Cytokine profiling at disease onset: support for classification of young antinuclear antibody-positive patients as a separate category of juvenile idiopathic arthritis

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  • Funding The authors have received funding (project acronym EUTrain) from the 7th Framework programme of the EU, SP3-People, support for training and career development for researchers (Marie Curie), Network for Initial Training (ITN), FP7-PEOPLE-2011-ITN, under the Marie Skłodowska-Curie grant agreement No 289903, and the Dutch Arthritis Association.

  • Contributors TB, EH, HO, AM, BP and WJ: study design, drafting and revising the article; TvdB, WJ: statistical analysis; JM, RS and HO: lab analysis. EH, JS and BP: patient recruitment. All authors contributed to the development and critical review of the manuscript and approved the final version.

  • Competing interests None.

  • Ethics approval Local medical ethical committee of University Medical Center of Utrecht and Nijmegen.

  • Provenance and peer review Not commissioned; externally peer reviewed.