Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss

Jean-Pierre Pelletier; Camille Roubille; Jean-Pierre Raynauld; François Abram; Marc Dorais; Philippe Delorme; Johanne Martel-Pelletier

doi:10.1136/annrheumdis-2013-203989

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Clinical and epidemiological research

Extended report

Disease-modifying effect of strontium ranelate in a subset of patients from the Phase III knee osteoarthritis study SEKOIA using quantitative MRI: reduction in bone marrow lesions protects against cartilage loss

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	Abstract	Full	Pdf
Dec 2013	448	56	71
Jan 2014	192	37	40
Feb 2014	149	10	11
Mar 2014	102	16	13
Apr 2014	68	14	14
May 2014	67	4	4
Jun 2014	31	4	7
Jul 2014	26	2	4
Aug 2014	25	3	3
Sep 2014	51	7	9
Oct 2014	39	1	5
Nov 2014	39	13	14
Dec 2014	28	3	6
Jan 2015	959	25	76
Feb 2015	495	19	45
Mar 2015	266	25	31
Apr 2015	125	11	20
May 2015	260	5	13
Jun 2015	99	9	12
Jul 2015	75	8	11
Aug 2015	60	5	12
Sep 2015	191	13	12
Oct 2015	275	2	5
Nov 2015	484	8	11
Dec 2015	152	6	14
Jan 2016	86	7	8
Feb 2016	103	2	5
Mar 2016	81	15	15
Apr 2016	55	8	10
May 2016	69	12	9
Jun 2016	58	7	5
Jul 2016	48	7	9
Aug 2016	59	4	6
Sep 2016	95	8	50
Oct 2016	48	5	2
Nov 2016	47	6	6
Dec 2016	56	6	4
Jan 2017	43	11	9
Feb 2017	45	9	8
Mar 2017	42	8	10
Apr 2017	40	0	2
May 2017	73	12	10
Jun 2017	58	1	2
Jul 2017	120	10	8
Aug 2017	118	6	17
Sep 2017	103	7	7
Oct 2017	81	7	7
Nov 2017	88	6	7
Dec 2017	65	2	1
Jan 2018	69	8	4
Feb 2018	95	3	4
Mar 2018	134	7	4
Apr 2018	63	7	3
May 2018	81	3	4
Jun 2018	44	1	1
Jul 2018	97	11	10
Aug 2018	52	11	7
Sep 2018	55	9	4
Oct 2018	42	4	2
Nov 2018	66	4	5
Dec 2018	54	3	2
Jan 2019	56	3	3
Feb 2019	29	4	5
Mar 2019	42	4	4
Apr 2019	38	3	4
May 2019	40	3	3
Jun 2019	42	2	0
Jul 2019	62	12	5
Aug 2019	26	0	0
Sep 2019	47	4	3
Oct 2019	55	7	2
Nov 2019	76	10	6
Dec 2019	50	4	7
Jan 2020	50	4	4
Feb 2020	46	3	2
Mar 2020	27	3	0
Apr 2020	42	4	2
May 2020	54	4	4
Jun 2020	52	6	5
Jul 2020	74	4	5
Aug 2020	84	2	2
Sep 2020	124	5	5
Oct 2020	88	1	1
Nov 2020	56	3	3
Dec 2020	77	5	3
Jan 2021	51	1	1
Feb 2021	57	2	3
Mar 2021	52	2	0
Apr 2021	58	2	0
May 2021	30	2	1
Jun 2021	1	0	2
Jul 2021	2	2	3
Aug 2021	1	1	1
Sep 2021	2	2	1
Oct 2021	71	4	0
Nov 2021	92	7	9
Dec 2021	33	2	0
Jan 2022	61	8	1
Feb 2022	70	4	2
Mar 2022	51	3	1
Apr 2022	40	4	4
May 2022	85	3	1
Jun 2022	110	7	6
Jul 2022	62	2	1
Total	9505	701	845

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