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Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin

Authors

  • Wen-Hung Chung Department of Dermatology, Keelung Chang Gung Memorial Hospital, Keelung, Taiwan Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan College of Medicine, Chang Gung University, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Wan-Chun Chang Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan PubMed articlesGoogle scholar articles
  • Sophie L Stocker Department of Clinical Pharmacology & Toxicology, St. Vincent's Hospital, Sydney, New South Wales, Australia St Vincent’s Hospital Clinical School and School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Chiun-Gung Juo Molecular Medicine Research Center, Chang Gung University, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Garry G Graham Department of Clinical Pharmacology & Toxicology, St. Vincent's Hospital, Sydney, New South Wales, Australia St Vincent’s Hospital Clinical School and School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Ming-Han H Lee Department of Clinical Pharmacology & Toxicology, St. Vincent's Hospital, Sydney, New South Wales, Australia St Vincent’s Hospital Clinical School and School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Kenneth M Williams Department of Clinical Pharmacology & Toxicology, St. Vincent's Hospital, Sydney, New South Wales, Australia St Vincent’s Hospital Clinical School and School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Ya-Chung Tian College of Medicine, Chang Gung University, Taoyuan, Taiwan Department of Nephrology, Kidney Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Kuo-Chang Juan College of Medicine, Chang Gung University, Taoyuan, Taiwan Department of Nephrology, Kidney Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Yeong-Jian Jan Wu College of Medicine, Chang Gung University, Taoyuan, Taiwan Division of Allergy, Immunology and Rheumatology, Department of Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan PubMed articlesGoogle scholar articles
  • Chih-Hsun Yang Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan College of Medicine, Chang Gung University, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Chee-Jen Chang Graduate Institute of Clinical Medical Science, Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan, Taiwan Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Yu-Jr Lin Graduate Institute of Clinical Medical Science, Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan, Taiwan Biostatistical Center for Clinical Research, Chang Gung Memorial Hospital, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Richard O Day Department of Clinical Pharmacology & Toxicology, St. Vincent's Hospital, Sydney, New South Wales, Australia St Vincent’s Hospital Clinical School and School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia PubMed articlesGoogle scholar articles
  • Shuen-Iu Hung Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Shuen-Iu Hung, Institute of Pharmacology, National Yang-Ming University, 155, Linong Street, Section 2, Beitou, Taipei 11221, Taiwan; sihung@ym.edu.tw Dr Richard O Day, Department of Clinical Pharmacology & Toxicology, St Vincent's Hospital, Sydney, New South Wales, Australia; r.day{at}unsw.edu.au
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Citation

Chung W, Chang W, Stocker SL, et al
Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin

Publication history

  • Received March 17, 2014
  • Revised June 29, 2014
  • Accepted July 26, 2014
  • First published August 12, 2014.
Online issue publication 
March 02, 2022

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