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Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice
  1. Min-jun Huang1,2,
  2. Liang Wang1,2,
  3. Da-di Jin1,2,
  4. Zhong-min Zhang1,2,
  5. Tian-yu Chen1,2,
  6. Chun-hong Jia3,
  7. Yan Wang4,
  8. Xiao-chen Zhen1,2,
  9. Bin Huang1,2,
  10. Bo Yan1,2,
  11. Yu-hui Chen1,2,
  12. Sheng-fa Li1,2,
  13. Jin-cheng Yang5,
  14. Yi-fan Dai4,
  15. Xiao-chun Bai2,3
  1. 1Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China
  2. 2Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China
  3. 3Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, PR China
  4. 4The Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu, PR China
  5. 5Department of Orthopedics, Liu Hua Qiao Hospital, Guangzhou, Guangdong, PR China
  1. Correspondence to Dr Xiao-chun Bai, Department of Cell Biology, School of Basic Medical Science, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou 510515, China; baixc15{at}smu.edu.cn

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