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Contributors All authors were involved in drafting the article or revising it critically for important intellectual content, and all authors approved the final version.
Funding This work was supported by ‘Gums & Joints’, a European Union FP7 Grant FP7 HEALTH-F2-2010-261460 and ‘RAPID’, a European Union funded ITN project 290246.
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.
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