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IgG4-related midline destructive lesion

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  • Contributors ED-T and JHS conceived of and conducted the clinical studies. HM and VSM conducted laboratory studies with guidance from SP. DK and PS helped with clinical diagnosis and management of patients. VD helped with pathological diagnosis of patients. ED-T and JHS drafted the manuscript. All authors read and approved the final version.

  • Funding This study was funded by grants AI 064930 and AI 076505 from the NIH and a pilot grant from the Harvard Institute of Translational Immunology supported by the Helmsley Foundation.

  • Competing interests None.

  • Ethics approval This study involves human subjects and was approved by the Ethics Committee/Institutional Review Board of the Massachusetts General Hospital (Partners).