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Contributors GPRC devised the study, wrote protocol, made submissions to ethics and MHRA and was acting CI. He wrote the paper with AG. He submitted to the journal. JSHG was official CI. PO'C and AG reported the MRIs. PWB and SJG were local radiologists reporting baseline scans for recruitment purposes. SB and AG helped recruit patients and run (as consecutive PIs) the study at one centre.
Funding The study was made possible by an unrestricted grant awarded to Dr Clunie by Novartis. Novartis had no part in the study design or the collection, analysis or interpretation of the data nor in the writing of the report or in the decision to submit the paper for publication.
Competing interests None.
Ethics approval Cambridgeshire 4 Research Ethics Committee.
Provenance and peer review Not commissioned; externally peer reviewed.
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