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Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

Authors

  • Rebeccah J Mathews Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK PubMed articlesGoogle scholar articles
  • James I Robinson Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK PubMed articlesGoogle scholar articles
  • Michele Battellino Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK Rheumatology Unit, L. Sacco University Hospital, Milan, Italy PubMed articlesGoogle scholar articles
  • Chi Wong Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK PubMed articlesGoogle scholar articles
  • John C Taylor NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK Institute of Cancer Studies and Pathology, The University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, ARC-EU, Stopford Building, Manchester, UK Google scholar articles
  • Steve Eyre Arthritis Research UK-Epidemiology Unit, The University of Manchester, Manchester, UK PubMed articlesGoogle scholar articles
  • Sarah M Churchman Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK PubMed articlesGoogle scholar articles
  • Anthony G Wilson Department of Infection and Immunity, The University of Sheffield, Sheffield, UK PubMed articlesGoogle scholar articles
  • John D Isaacs Musculoskeletal Research Group, Institute of Cellular Medicine, The Medical School, Newcastle University, UK National Institute for Health Research Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Kimme Hyrich Arthritis Research UK-Epidemiology Unit, The University of Manchester, Manchester, UK PubMed articlesGoogle scholar articles
  • Anne Barton Arthritis Research UK-Epidemiology Unit, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK PubMed articlesGoogle scholar articles
  • Darren Plant NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK PubMed articlesGoogle scholar articles
  • Sinisa Savic NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK Department of Clinical Immunology and Allergy, The University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Graham P Cook NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK Institute of Cancer Studies and Pathology, The University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Piercarlo Sarzi-Puttini Rheumatology Unit, L. Sacco University Hospital, Milan, Italy PubMed articlesGoogle scholar articles
  • Paul Emery Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK PubMed articlesGoogle scholar articles
  • Jennifer H Barrett NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK Institute of Cancer Studies and Pathology, The University of Leeds, Leeds, UK PubMed articlesGoogle scholar articles
  • Ann W Morgan Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK PubMed articlesGoogle scholar articles
  • Michael F McDermott Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, Chapel Allerton Hospital, UK NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Michael McDermott, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Wellcome Trust Brenner Building, St. James's University Hospital, Leeds LS9 7TF, UK; m.mcdermott{at}leeds.ac.uk
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Citation

Mathews RJ, Robinson JI, Battellino M, et al
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment

Publication history

  • Accepted April 14, 2013
  • First published May 17, 2013.
Online issue publication 
April 30, 2014

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