Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein

Stacy P Ardoin; Laura Eve Schanberg; Christy I Sandborg; Huiman X Barnhart; Greg W Evans; Eric Yow; Kelly L Mieszkalski; Norman T Ilowite; Anne Eberhard; Lisa F Imundo; Yuki Kimura; Deborah Levy; Emily von Scheven; Earl Silverman; Suzanne L Bowyer; L Punaro; Nora G Singer; David D Sherry; Deborah K McCurdy; Marissa Klein-Gitelman; Carol Wallace; Richard M Silver; Linda Wagner-Weiner; Gloria C Higgins; Hermine I Brunner; Lawrence Jung; Jennifer B Soep; Ann M Reed; Susan D Thompson; for the APPLE investigators

doi:10.1136/annrheumdis-2012-202315

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Clinical and epidemiological research

Extended report

Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein

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	Abstract	Full	Pdf
Feb 2013	235	30	51
Mar 2013	203	30	29
Apr 2013	138	17	14
May 2013	130	16	19
Jun 2013	113	4	7
Jul 2013	99	8	13
Aug 2013	112	5	7
Sep 2013	58	15	15
Oct 2013	31	10	8
Nov 2013	37	7	10
Dec 2013	36	4	4
Jan 2014	20	7	7
Feb 2014	1132	33	95
Mar 2014	476	20	43
Apr 2014	261	10	25
May 2014	157	16	18
Jun 2014	87	5	6
Jul 2014	70	6	5
Aug 2014	88	4	9
Sep 2014	74	8	11
Oct 2014	58	9	8
Nov 2014	51	4	4
Dec 2014	36	5	8
Jan 2015	53	6	8
Feb 2015	34	4	3
Mar 2015	38	11	15
Apr 2015	40	8	7
May 2015	32	9	6
Jun 2015	35	5	4
Jul 2015	15	4	2
Aug 2015	28	5	3
Sep 2015	45	5	4
Oct 2015	28	1	1
Nov 2015	24	4	2
Dec 2015	46	4	2
Jan 2016	58	1	1
Feb 2016	73	1	3
Mar 2016	27	2	2
Apr 2016	38	2	1
May 2016	39	1	4
Jun 2016	39	2	5
Jul 2016	22	2	2
Aug 2016	23	6	4
Sep 2016	34	2	4
Oct 2016	40	5	9
Nov 2016	29	2	4
Dec 2016	13	0	0
Jan 2017	25	1	1
Feb 2017	23	7	5
Mar 2017	27	1	3
Apr 2017	15	2	1
May 2017	39	1	3
Jun 2017	30	2	1
Jul 2017	56	4	5
Aug 2017	76	6	8
Sep 2017	65	4	6
Oct 2017	62	2	2
Nov 2017	50	2	4
Dec 2017	93	5	2
Jan 2018	43	4	0
Feb 2018	58	1	2
Mar 2018	33	5	5
Apr 2018	39	6	3
May 2018	25	3	2
Jun 2018	65	6	2
Jul 2018	60	6	3
Aug 2018	33	2	1
Sep 2018	39	2	0
Oct 2018	64	2	1
Nov 2018	37	2	2
Dec 2018	50	3	1
Jan 2019	40	6	2
Feb 2019	51	3	4
Mar 2019	46	0	0
Apr 2019	18	0	0
May 2019	27	1	0
Jun 2019	25	5	5
Jul 2019	32	4	1
Aug 2019	26	0	0
Sep 2019	24	2	1
Oct 2019	46	2	1
Nov 2019	26	3	3
Dec 2019	21	1	1
Jan 2020	34	3	1
Feb 2020	43	4	2
Mar 2020	21	7	3
Apr 2020	29	9	3
May 2020	39	5	1
Jun 2020	24	4	0
Jul 2020	29	5	0
Aug 2020	41	1	0
Sep 2020	50	3	1
Oct 2020	45	2	1
Nov 2020	56	1	0
Dec 2020	34	2	1
Jan 2021	31	1	0
Feb 2021	37	3	1
Mar 2021	40	6	1
Apr 2021	46	6	3
May 2021	21	3	1
Jun 2021	5	5	0
Jul 2021	2	2	5
Aug 2021	2	1	0
Sep 2021	5	3	1
Oct 2021	39	3	0
Nov 2021	38	2	1
Dec 2021	51	1	0
Jan 2022	47	1	0
Feb 2022	62	5	1
Mar 2022	81	5	1
Apr 2022	115	3	1
May 2022	90	2	0
Jun 2022	88	7	1
Jul 2022	47	3	2
Aug 2022	74	1	0
Sep 2022	138	6	1
Oct 2022	90	10	1
Nov 2022	106	3	2
Dec 2022	75	6	0
Jan 2023	83	2	1
Feb 2023	75	3	1
Mar 2023	91	3	1
Apr 2023	30	5	2
May 2023	53	5	1
Jun 2023	28	1	1
Jul 2023	30	3	0
Aug 2023	43	3	1
Sep 2023	40	4	0
Oct 2023	50	4	0
Nov 2023	63	10	1
Dec 2023	75	2	1
Jan 2024	59	6	3
Feb 2024	34	1	0
Mar 2024	56	5	3
Total	8629	662	645

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