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Subsets of RP105-negative plasmablasts in IgG4-related disease
  1. Syuichi Koarada,
  2. Satoko Tashiro,
  3. Yukiko Tokuda,
  4. Yukihide Ono,
  5. Yuri Sadanaga,
  6. Rie Suematsu,
  7. Nobuyuki Ono,
  8. Akihide Ohta,
  9. Yoshifumi Tada
  1. Correspondence to Dr Syuichi Koarada, Division of Rheumatology, Faculty of Medicine, Saga University, Saga 849-8501, Japan; koarada{at}

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We read with interest the paper by Wallace ZS, plasmablasts as a biomarker for IgG4-related disease (IgG4-RD), independent of serum IgG4 concentrations.1 Evidently, the study showed that patients with active, untreated IgG4-RD have elevations in their circulating plasmablast counts. We strongly approve their results and propose new insights into plasmablast subsets in …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; internally peer reviewed.