Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study)

J L Nam; E Villeneuve; E M A Hensor; P G Conaghan; H I Keen; M H Buch; A K Gough; M J Green; P S Helliwell; A M Keenan; A W Morgan; M Quinn; R Reece; D M van der Heijde; R J Wakefield; P Emery

doi:10.1136/annrheumdis-2013-203440

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Clinical and epidemiological research

Extended report

Remission induction comparing infliximab and high-dose intravenous steroid, followed by treat-to-target: a double-blind, randomised, controlled trial in new-onset, treatment-naive, rheumatoid arthritis (the IDEA study)

Authors

J L Nam Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
E Villeneuve Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
E M A Hensor Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
P G Conaghan Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
H I Keen School of Medicine and Pharmacology Royal Perth Hospital Unit, The University of Western Australia, Perth, Western Australia, Australia PubMed articles Google scholar articles
M H Buch Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
A K Gough Rheumatology Department, Harrogate District Foundation Trust, Harrogate, UK PubMed articles Google scholar articles
M J Green Department of Rheumatology, York Hospital NHS Foundation Trust, York, UK PubMed articles Google scholar articles
P S Helliwell Division of Musculoskeletal Disease, University of Leeds, Leeds, UK PubMed articles Google scholar articles
A M Keenan Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
A W Morgan Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
M Quinn Department of Rheumatology, York Hospital NHS Foundation Trust, York, UK PubMed articles Google scholar articles
R Reece Division of Musculoskeletal Disease, University of Leeds, Leeds, UK PubMed articles Google scholar articles
D M van der Heijde Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
R J Wakefield Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles
P Emery Institute Rheumatic and Musculoskeletal Medicine, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK PubMed articles Google scholar articles

Correspondence to Professor P Emery, Division of Rheumatic and Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, LTHT, Leeds, UK; p.emery{at}leeds.ac.uk

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Citation

Nam JL, Villeneuve E, Hensor EMA, et al

Annals of the Rheumatic Diseases 2014;73:75-85.

Publication history

Received February 8, 2013
Revised June 3, 2013
Accepted July 9, 2013
First published August 2, 2013.

Online issue publication

December 04, 2013

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