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Population-specific effects of SLC17A1 genotype on serum urate concentrations and renal excretion of uric acid during a fructose load

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Footnotes

  • Clinical Trials Registration The study was registered by the Australian Clinical Trials Registry (ACTRN12610001036000).

  • Contributors ND (the guarantor) accepts full responsibility for the work and the conduct of the study, had access to the data, and controlled the decision to publish. ND conceived of the study, contributed to the data interpretation, and drafted the manuscript. MEH, AH, LP and AS recruited participants and coordinated study visits. MEH also managed clinical data entry. MM, MC and APG contributed to data acquisition and genetic data entry. GDG analysed the data. TRM conceived of the study, contributed to the data interpretation, and drafted the manuscript. All authors read and approved the final manuscript.

  • Funding This study was funded by the Health Research Council of New Zealand (grant number 11/1075).

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval The study received ethics approval from the New Zealand Ministry of Health Multiregional Ethics Committee.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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