Background Evaluation of disease activity is essential in decision of the treatment and monitoring the therapies in rheumatoid arthritis (RA). Rheumatoid Arthritis Disease Activity Index (RADAI) appears as an attractive form in determining the disease activity in RA patients especially in busy clinical settings, as it comprises current and past disease activity and morning stiffness.
Objectives The aim of this study was to evaluate the disease activity by RADAI and determine the correlation to other disease activity indexes like Disease Activity Score 28 (DAS28), Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI).
Methods Ninty-seven Turkish patients with RA were recruited from the PMR clinic, and demographic characteristics were recorded. The clinical and laboratory parameters including joint count, health assesment questionnaire (HAQ), ESR and CRP. All patients completed the activity forms comprising RADAI, CDAI, SDAI and DAS 28.
Results Ninty-seven patients with a mean age 3.86±11.03 and disease duration of 15.7±14.8 years respectively, were included. The mean scores of RADAI, CDAI, SDAI and DAS 28 were 2.4±1.9, 9.6±7.1, 10.2±7.3 and 2.8±0.9 respectively. According to RADAI assessment there were 4 patients on moderate activity,28 patients on low activity and 65patients on remisison. The percentage of patients with high/moderate/low/remission according to CDAI, SDAI and DAS28, were 4.1%/32.9%/42.2%/20.6%; 0/12.3%/63.9%/23.7%; and 0/29.8%/27.8%/42.2%, respectively. The most correlated index with RADAI was determined as CDAI (p<0.05, r=0.791) and SDAI (p<0.05, r=0769).
Conclusions The RADAI scores provide comparable and similar quantitative information to CDAI, SDAI and DAS28 in a group of Turkish RA patients. We suggest this comprehensive assessment index especially in disease evaluation over time in RA patients’ management. Also we hope our data help to make comparisons between RA patients from different cultures.
Disclosure of Interest None Declared
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